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Title:
1,5-BENZODIAZEPINE COMPOUND CRYSTAL
Document Type and Number:
WIPO Patent Application WO/2017/175854
Kind Code:
A1
Abstract:
The present invention provides a novel crystal of a compound A, the novel crystal being usable as a pharmaceutical product. Provided is a IV-type crystal of calcium (R)-(-)-3-[3-(1-tert-butylcarbonylmethyl-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl)ureido]benzoate characterized by having characteristic peaks at diffraction angles (2θ±0.2°) of 7.94°, 8.50°, 10.27°, 12.30°, 12.83°, 13.93°, 17.19°, 19.04°, 20.57°, and 23.94° in a powder X-ray diffraction spectrum.

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Inventors:
NAKAO RYU (JP)
Application Number:
PCT/JP2017/014486
Publication Date:
October 12, 2017
Filing Date:
April 07, 2017
Export Citation:
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Assignee:
ZERIA PHARM CO LTD (JP)
International Classes:
C07D243/12; A61K31/551; A61P1/04
Domestic Patent References:
WO2001040197A12001-06-07
WO1998025911A11998-06-18
Other References:
HIRAYAMA: "Yuki Kagobutsu Kessho Sakusei Handbook", 2008, KODANSHA LTD, Tokyo, ISBN: 978-4-621-07991-1
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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