Title:
(3Β)-17-(1H-BENZIMIDAZOLE-1-YL)ANDROSTANE-5, AND 16-DIENE-3-OL SALTS AND PREPARATION METHODS THEREFOR
Document Type and Number:
WIPO Patent Application WO/2016/119742
Kind Code:
A1
Abstract:
The present invention relates to crystalline forms of (3β)-17-(1H-benzimidazole-1-yl)androstane-5, and 16-diene-3-ol phosphate, tartrate, and citrate and preparation methods therefor. Crystalline forms of phosphate, tartrate, and citrate of a compound of formula (I) in the present invention have advantageous performance such as high solubility, low hygroscopicity, good stability, a simple process, and being easy to operate, are suitable for storage and industrialized production, and have an important value in future optimization and development of the drug.
Inventors:
CHEN MINHUA (CN)
ZHANG YANFENG (CN)
DIAO XIAOJUAN (CN)
XIA NAN (CN)
ZHANG XIAOYU (CN)
ZHANG YANFENG (CN)
DIAO XIAOJUAN (CN)
XIA NAN (CN)
ZHANG XIAOYU (CN)
Application Number:
PCT/CN2016/072729
Publication Date:
August 04, 2016
Filing Date:
January 29, 2016
Export Citation:
Assignee:
CRYSTAL PHARMATECH CO LTD (CN)
International Classes:
C07J43/00; A61K31/58; A61P13/08; A61P35/00
Domestic Patent References:
| WO2011017534A2 | 2011-02-10 | |||
| WO2013096907A1 | 2013-06-27 | |||
| WO2010091299A2 | 2010-08-12 |
Foreign References:
| CN103813794A | 2014-05-21 | |||
| CN102822190A | 2012-12-12 |
Attorney, Agent or Firm:
SUZHOU CREATOR PATENT & TREADMARK AGENCY LTD. (CN)
苏州创元专利商标事务所有限公司 (CN)
苏州创元专利商标事务所有限公司 (CN)
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