Title:
17-METHYLENE-OR 17 - SPIRO - CYCLOPROPANE 7 - SUBSTITUTED ESTRA - 1, 3, 5 (10) - TRIENE DERIVATIVES WITH ANTI - ESTROGENIC ACTIVITY
Document Type and Number:
WIPO Patent Application WO2005077968
Kind Code:
B1
Abstract:
The present invention relates to novel compounds which are 7alpha-substituted 17-alkylene-16 alpha-hydroxy steroidal estrogens (see formula I). This invention specifically relates to estrogen derivatives which contain 7 alpha -substituents and which exhibit anti-estrogenic properties. The present invention also relates to use of said compounds as a medicament, and for the treatment of estrogen dependent disorders, a pharmaceutical composition comprising one or more of said compounds and a method of treatment.
Inventors:
PETTERSSON LARS (SE)
Application Number:
PCT/SE2005/000188
Publication Date:
January 04, 2007
Filing Date:
February 11, 2005
Export Citation:
Assignee:
INNOVENTUS PROJECT AB (SE)
PETTERSSON LARS (SE)
PETTERSSON LARS (SE)
International Classes:
C07J13/00; A61K31/56; A61K31/57; A61P5/32; C07J3/00; C07J31/00; C07J41/00; C07J53/00; C07D
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