2-`3-AMINO-4-(N-HYDROXYAMINO)-SUCCINYLAMINO-ACETAMIDES FOR USE AS CD23 FORMATION INHIBITORS

Title:

2-`3-AMINO-4-(N-HYDROXYAMINO)-SUCCINYLAMINO-ACETAMIDES FOR USE AS CD23 FORMATION INHIBITORS

Document Type and Number:

WIPO Patent Application WO2001049657

Kind Code:

A8

Abstract:

Compounds of formula (I): wherein X<1> is alkyl, sulphonyl or carboxy; X<2> is hydrogen or alkyl; R<1> is arylmethyl or heterocyclylmethyl; R<2> is alkyl, alkenyl, aryl, cycloalkyl or cycloalkenyl; and R<3> is hydrogen, alkyl, alkenyl, alkynyl or aryl; are useful in the treatment of disorders mediated by s-CD23.

Inventors:

FALLER ANDREW (GB)
ROUSSEAU ANNE-GERALDINE (GB)
MACPHERSON DAVID TIMOTHY (GB)
MILNER PETER HENRY (GB)

Application Number:

PCT/GB2000/005012

Publication Date:

November 08, 2001

Filing Date:

December 22, 2000

Export Citation:

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Assignee:

SMITHKLINE BEECHAM PLC (GB)
FALLER ANDREW (GB)
ROUSSEAU ANNE GERALDINE (GB)
MACPHERSON DAVID TIMOTHY (GB)
MILNER PETER HENRY (GB)

International Classes:

A61K31/16; A61K31/165; A61K31/18; A61P37/02; A61P37/08; A61P29/00; A61P43/00; C07C259/06; C07C303/38; C07C311/13; C07D307/52; (IPC1-7): C07C259/06; C07C311/13; C07D307/52; A61K37/00; A61K31/16

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