Title:
2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS
Document Type and Number:
WIPO Patent Application WO/1997/009301
Kind Code:
A1
Abstract:
2-Acylbenzamide derivatives represented by general formula (I), (wherein R1, R2, R3, R4 and R5 represent each hydrogen, etc.; X represents vinylene, etc.; and B represents -N(R6) (R7) (wherein R6 and R7 represent each hydrogen, etc.), -NH-(CH2)n-A-R8 (wherein A represents a single bond, etc.; and R8 represents hydroxy, etc.) or hydroxyamino, which is useful as a preventive and remedy for diseases caused by the supermultiplication of vascular intimal cells.
Inventors:
HARADA HIROMU (JP)
KUSAMA HIROSHI (JP)
NONAKA YOSHINORI (JP)
KAMATA KOJI (JP)
HOTEI YUKIHIKO (JP)
IYOBE AKIRA (JP)
FUJIKURA HIDEKI (JP)
SATOH FUMIYASU (JP)
KUSAMA HIROSHI (JP)
NONAKA YOSHINORI (JP)
KAMATA KOJI (JP)
HOTEI YUKIHIKO (JP)
IYOBE AKIRA (JP)
FUJIKURA HIDEKI (JP)
SATOH FUMIYASU (JP)
Application Number:
PCT/JP1996/002415
Publication Date:
March 13, 1997
Filing Date:
August 29, 1996
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL (JP)
HARADA HIROMU (JP)
KUSAMA HIROSHI (JP)
NONAKA YOSHINORI (JP)
KAMATA KOJI (JP)
HOTEI YUKIHIKO (JP)
IYOBE AKIRA (JP)
FUJIKURA HIDEKI (JP)
SATOH FUMIYASU (JP)
HARADA HIROMU (JP)
KUSAMA HIROSHI (JP)
NONAKA YOSHINORI (JP)
KAMATA KOJI (JP)
HOTEI YUKIHIKO (JP)
IYOBE AKIRA (JP)
FUJIKURA HIDEKI (JP)
SATOH FUMIYASU (JP)
International Classes:
C07C237/42; C07C255/41; C07C255/57; C07C259/10; C07C317/44; (IPC1-7): C07C237/42; A61K31/165
Foreign References:
| JPS6426543A | 1989-01-27 | |||
| JPS6136273A | 1986-02-20 |
Other References:
See also references of EP 0855387A4
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