Title:
2-AMINO-2-(1,2,3-TRIAZOLE-4-YL)PROPANE-1,3-DIOL DERIVATIVE OF NOVEL COMPOUND FOR DIRECTLY INHIBITING ASM ACTIVITY, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/212196
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing or treating neurodegenerative diseases or depression, containing a 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative as an active ingredient and, more specifically, to a pharmaceutical composition for preventing or treating neurodegenerative diseases or depression, containing, as an active ingredient, a compound having an effect of directly inhibiting ASM activity.
Inventors:
BAE JAE-SUNG (KR)
JIN HEE KYUNG (KR)
PARK MIN HEE (KR)
JIN HEE KYUNG (KR)
PARK MIN HEE (KR)
Application Number:
PCT/KR2019/005019
Publication Date:
November 07, 2019
Filing Date:
April 25, 2019
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR)
International Classes:
C07D249/04; A61K31/4192; A61P25/00; A61P25/24
Domestic Patent References:
| WO2010017408A1 | 2010-02-11 |
Foreign References:
| KR20170087813A | 2017-07-31 | |||
| KR20180036318A | 2018-04-09 | |||
| KR101811436B1 | 2017-12-21 | |||
| US20170119912A1 | 2017-05-04 | |||
| KR20180050215A | 2018-05-14 | |||
| KR101521117B1 | 2015-05-18 |
Other References:
NATURE MEDICINE, vol. 19, no. 7, July 2013 (2013-07-01), pages 934 - 938
PLOS ONE, vol. 11, no. 9, 6 September 2016 (2016-09-06), pages e0162498
NEUROBIOLOGY OF AGING, vol. 31, 2010, pages 398 - 408
SCIENTIFIC REPORT, vol. 8, 2018, pages 3071
BIOCHEM BIOPHYS RES COMMUN, vol. 404, no. 1, 7 January 2011 (2011-01-07), pages 321 - 323
See also references of EP 3789380A4
PLOS ONE, vol. 11, no. 9, 6 September 2016 (2016-09-06), pages e0162498
NEUROBIOLOGY OF AGING, vol. 31, 2010, pages 398 - 408
SCIENTIFIC REPORT, vol. 8, 2018, pages 3071
BIOCHEM BIOPHYS RES COMMUN, vol. 404, no. 1, 7 January 2011 (2011-01-07), pages 321 - 323
See also references of EP 3789380A4
Attorney, Agent or Firm:
LEE, Hee Sook (KR)
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