2-CYANOPYRROLOPYRIMIDINES AND PHARMACEUTICAL USES THEREOF

WIPO Patent Application WO2004069256

A8

The invention relates to pyrrolo pyrimidines of formula (I), wherein Y represents -(CH2)t-O- or -(CH2)r-S-, p is 1 or 2, r is 1, 2 or 3, t is 1, 2 or 3, or Y is -(CH2)j- or -CH=CH-, j is 1 or 2; p is 1 or 2, or Y is -(CH2)f-, f is 1 or 2, p is 1, and the further radicals and symbols have the meaning as defined herein; their preparation, their use as pharmaceuticals, pharmaceutical compositions containing them, the use of such a compound for the manufacture of a pharmaceutical preparation for the treatment of neuropathic pain and to a method for the treatment of such a disease in animals, especially in humans.

BUXTON FRANCIS PAUL (US)
EHARA TAKERU (JP)
GANJU PAMPOSH (GB)
HALLETT ALLAN (GB)
IRIE OZAMU (JP)
IWASAKI ATSUKO (JP)
KANAZAWA TAKANORI (JP)
MASUYA KEIICHI (JP)
NONOMURA KAZUHIKO (JP)
SAKAKI JUNICHI (JP)
SNELL CHRISTOPHER ROBERT (GB)
SONG CHUANHENG (US)
TANABE KEIKO (JP)
TENO NAOKI (JP)
UMEMURA ICHIRO (JP)
YOKOKAWA FUMIAKI (JP)

PCT/EP2004/001081

October 14, 2004

February 05, 2004

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NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
BUXTON FRANCIS PAUL (US)
EHARA TAKERU (JP)
GANJU PAMPOSH (GB)
HALLETT ALLAN (GB)
IRIE OZAMU (JP)
IWASAKI ATSUKO (JP)
KANAZAWA TAKANORI (JP)
MASUYA KEIICHI (JP)
NONOMURA KAZUHIKO (JP)
SAKAKI JUNICHI (JP)
SNELL CHRISTOPHER ROBERT (GB)
SONG CHUANHENG (US)
TANABE KEIKO (JP)
TENO NAOKI (JP)
UMEMURA ICHIRO (JP)
YOKOKAWA FUMIAKI (JP)

A61P29/00; C07D487/04; C07D519/00; (IPC1-7): A61K31/519; A61P29/00; C07D487/04

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