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Patent Searching and Data


Title:
2-FUCOSYLLACTOSE PRODUCING MUTANT MICROORGANISMS AND METHOD FOR PRODUCING 2-FUCOSYLLACTOSE USING SAME
Document Type and Number:
WIPO Patent Application WO/2016/153300
Kind Code:
A1
Abstract:
The present invention relates to mutant microorganisms for producing 2-fucosyllactose and a method for producing 2-fucosyllactose using the same and, more specifically, to mutant microorganisms into which a lacZ-modified or removed operon is introduced and at least one gene selected from the group consisting of genes coding FucT2 or variants thereof and genes coding glucose-6-phosphate dehydrogenase (G6PDH) and guanosine-inosine kinase (GSK) is introduced or amplified, and to a method for producing 2-fucosyllactose using the same.

Inventors:
SEO JIN HO (KR)
CHIN YOUNG WOOK (KR)
KIM JI YEONG (KR)
Application Number:
PCT/KR2016/003013
Publication Date:
September 29, 2016
Filing Date:
March 24, 2016
Export Citation:
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Assignee:
UNIV SEOUL NAT R & DB FOUND (KR)
International Classes:
C12N15/63; C12N9/04; C12N9/10; C12N9/12; C12N15/70; C12P19/12; C12R1/19
Foreign References:
KR20110061520A2011-06-09
US20130122553A12013-05-16
US20140031541A12014-01-30
Other References:
LEE, WON - HEONG ET AL.: "Whole Cell Biosynthesis of a Functional Oligosaccharide, 2' -Fucosyltactose, using Engineered Escherichia Coli", MICROBIAL CELL FACTORIES, vol. 11, no. e48, 2012, pages 1 - 9, XP021115889
ROWLEY, DANIEL L. ET AL.: "Molecular Characterization of the Escherichia Coli K-1 2 Zwf Gene Encoding Glucose 6-Phosphate Dehydrogenase", JOURNAL OF BACTERIOLOGY, vol. 173, no. 3, 1991, pages 968 - 977, XP055316226
Attorney, Agent or Firm:
TAEDONG INTERNATIONAL PATENT&LAW FIRM (KR)
특허법인태동 (KR)
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