Title:
2'-NITROBENZYL-MODIFIED RIBONUCLEOTIDES
Document Type and Number:
WIPO Patent Application WO2005118608
Kind Code:
A3
Abstract:
This disclosure provides novel reversibly terminated ribonucleotides which can be used as a reagent for DNA sequencing reactions. Methods of sequencing nucleic acids using the disclsoed nucleotides are also provided.
Inventors:
PIEPENBURG OLAF (GB)
STEMPLE DEREK L (GB)
ARMES NIALL A (GB)
STEMPLE DEREK L (GB)
ARMES NIALL A (GB)
Application Number:
PCT/IB2005/002488
Publication Date:
April 27, 2006
Filing Date:
June 02, 2005
Export Citation:
Assignee:
ASM SCIENT INC (GB)
PIEPENBURG OLAF (GB)
STEMPLE DEREK L (GB)
ARMES NIALL A (GB)
PIEPENBURG OLAF (GB)
STEMPLE DEREK L (GB)
ARMES NIALL A (GB)
International Classes:
C07H19/04; C07H19/10; C07H19/20; C12Q1/68; C07H
Foreign References:
| US6136543A | 2000-10-24 |
Other References:
METZKER M L ET AL: "TERMINATION OF DNA SYNTHESIS BY NOVEL 3'-MODIFIED-DEOXYRIBONUCLEOSIDE 5'-TRIPHOSPHATES", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 22, no. 20, 1994, pages 4259 - 4267, XP001068669, ISSN: 0305-1048
SHIN, SEUNGJIN ET AL: "Synthesis and photoaffinity labeling of 3'(2')-O-(p- azidobenzoyl )-ATP", JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY , 30(3), 211-215 CODEN: JBMBE5; ISSN: 1225-8687, 1997, XP009060719
SHIN, SEUNGJIN ET AL: "Synthesis and photoaffinity labeling of 3'(2')-O-(p- azidobenzoyl )-ATP", JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY , 30(3), 211-215 CODEN: JBMBE5; ISSN: 1225-8687, 1997, XP009060719
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