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Title:
2-O-α-D-MALTOSYL-L-ASCORBIC ACID-CONTAINING COMPOSITION AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2018/101431
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a 2-O-α-D-glycosyl-L-ascorbic acid composition which has excellent moisturizing properties and excellent skin wettability. The present invention relates to: a 2-O-α-D-maltosyl-L-ascorbic acid-containing composition which is a composition containing a 2-O-α-D-glycosyl-L-ascorbic acid represented by general formula (1) (wherein n represents an integer of 1 or more) or a salt thereof, and which is characterized in that 70% by mole or more of the 2-O-α-D-glycosyl-L-ascorbic acid is 2-O-α-D-maltosyl-L-ascorbic acid (n = 2); and a method for producing this 2-O-α-D-maltosyl-L-ascorbic acid-containing composition. This composition has excellent moisturizing properties and excellent skin wettability, and is useful as an external preparation for the skin.

Inventors:
UMEYAMA AKINORI (JP)
TAMURA MASAAKI (JP)
Application Number:
JP2017/043137
Publication Date:
June 07, 2018
Filing Date:
November 30, 2017
Export Citation:
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Assignee:
CARLIT HOLDINGS CO LTD (JP)
International Classes:
C12P19/22; A23L33/15; A61K8/67; A61K31/7048; A61P17/00; A61P17/16; A61Q19/00; C07H19/01; C12P19/18
Domestic Patent References:
WO2015046848A12015-04-02
Foreign References:
JPH05208991A1993-08-20
KR20030024934A2003-03-28
JP2010539105A2010-12-16
Other References:
AGA, H. ET AL.: "SYNTHESIS OF 2-O-ALPHA-D-GLUCOPYRANOSYL L-ASCORBIC ACID BY CYCLOMALTODEXTRIN GLUCANOTRANSFERASE FROM BACILLUS STEAROTHERMOPHILUS", AGRICULTURAL AND BIOLOGICAL CHEMISTRY, vol. 55, no. 7, 1991, pages 1751 - 1756, XP001029368
MARKOSYAN, A. A. ET AL.: "Transglycosylation of L-ascorbic acid", APPLIED BIOCHEMISTRY AND MICROBIOLOGY, vol. 43, no. 1, 1 February 2007 (2007-02-01), pages 36 - 40, XP019463547
BAE, H. -K. ET AL.: "Modification of ascorbic acid using transglycosylation activity of Bacillus stearothermophilus maltogenic amylase to enhance its oxidative stability", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 50, no. 11, 22 May 2002 (2002-05-22), pages 3309 - 3316, XP002269805
LEE, S. -B. ET AL.: "Antioxidative effects of glycosyl-ascorbic acids synthesized by maltogenic amylase to reduce lipid oxidation and volatiles production in cooked chicken meat,", BIOSCIENCE. BIOTECHNOLOGY. BIOCHEMISTRY, vol. 68, no. 1, 2004, pages 36 - 43, XP055512257
AHN, H. -J. ET AL.: "Enzymatic synthesis of 3-O-α-maltosyl-l-ascorbate using an engineered cyclodextrin glucanotransfe", FOOD CHEMISTRY, vol. 169, 2015, pages 366 - 371, XP029060438
Attorney, Agent or Firm:
SAEKI, Takuro et al. (JP)
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