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Title:
21-SUBSTITUTED STEROID COMPOUND
Document Type and Number:
WIPO Patent Application WO/1995/009177
Kind Code:
A1
Abstract:
A glycoside represented by formula (I), wherein dexamethasone or betamethasone is the aglycon and the 21-position is substituted by a simple sugar or an acylated sugar selected from the group consisting of glucose, galactose, mannose, rhamnose, fucose, N-acetylglucosamine, N-acetylgalactosamine, galacturonic acid, glucuronic acid and sialic acid.

Inventors:
SUGAI KEI (JP)
GOTO MOTOAKI (JP)
YOSHIDA SATOSHI (JP)
OKUNO YUMIKO (JP)
ISHII TAKAYUKI (JP)
KIBUSHI NOBUYUKI (JP)
NISHIKAWA HUTOSHI (JP)
Application Number:
PCT/JP1994/001602
Publication Date:
April 06, 1995
Filing Date:
September 28, 1994
Export Citation:
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Assignee:
KANTO ISHI PHARMA CO LTD (JP)
SUGAI KEI (JP)
GOTO MOTOAKI (JP)
YOSHIDA SATOSHI (JP)
OKUNO YUMIKO (JP)
ISHII TAKAYUKI (JP)
KIBUSHI NOBUYUKI (JP)
NISHIKAWA HUTOSHI (JP)
International Classes:
C07J17/00; C07J41/00; C07J43/00; (IPC1-7): C07J17/00; A61K31/705
Domestic Patent References:
WO1994015947A11994-07-21
Foreign References:
EP0123485A11984-10-31
Other References:
J. MED. CHEM., Vol. 27, No. 3, (1984), p. 261-266.
J. MED. CHEM., Vol. 28, No. 1, (1985), p. 51-57.
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