2,5-SUBSTITUTED BENZOLSULFONYLUREAS AND THIOUREAS, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

Title:

2,5-SUBSTITUTED BENZOLSULFONYLUREAS AND THIOUREAS, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

Document Type and Number:

WIPO Patent Application WO2000003978

Kind Code:

A3

Abstract:

The compounds of formula (I) act as inhibitors on ATP-sensitive potassium canals and are suitable for the treatment of cardio-vascular disorders, especially the treatment of arrhythmias, prevention of sudden death from heart disease or affect diminished contractility of the heart. The invention also relates to methods for producing compounds of formula (I), the use thereof and pharmaceutical preparations containing said compounds.

Inventors:

HEITSCH HOLGER (DE)
ENGLERT HEINRICH CHRISTIAN (DE)
GOEGELEIN HEINZ (DE)

Application Number:

PCT/EP1999/004643

Publication Date:

September 14, 2000

Filing Date:

July 03, 1999

Export Citation:

Click for automatic bibliography generation Help

Assignee:

AVENTIS PHARMA GMBH (DE)
HEITSCH HOLGER (DE)
ENGLERT HEINRICH CHRISTIAN (DE)
GOEGELEIN HEINZ (DE)

International Classes:

A61K31/18; A61K31/381; A61K31/4402; A61K31/4418; A61K31/64; A61P9/00; A61P9/06; A61P43/00; C07C311/00; C07D333/18; C07C311/58; C07C317/32; C07C323/67; C07C335/42; C07D213/40; C07D307/38; C07D307/52; C07D333/20; (IPC1-7): C07C335/42; C07C311/58; C07D333/20; C07D307/52; C07D213/40; A61K31/64; A61K31/38; A61K31/34; A61K31/44

Foreign References:

EP0657423A1	1995-06-14
EP0612724A1	1994-08-31

Download PDF:

View/Download PDF PDF Help

Previous Patent: ALPHA-(2-HYDROXYPHENYL) NITRONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR...

Next Patent: BENZOCYCLOHEPTENES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THESE ...