Title:
2,6-DIAZASPIRO[3.4]OCTANE PYRIMIDINE-HYDROXAMIC ACID COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/177128
Kind Code:
A1
Abstract:
Disclosed are a 2,6-diazaspiro[3.4]octane pyrimidine-hydroxamic acid compound and the use thereof. Specifically, the present invention relates to a compound as represented by formula I, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, and a preparation method therefor, and the use thereof in the preparation of HDAC inhibitor anti-malarial drugs.
Inventors:
LI JIAN (CN)
JIANG LUBIN (CN)
WANG MANJIONG (CN)
LI RUOXI (CN)
TANG TONGKE (CN)
LING DAZHENG (CN)
HUANG ZHENGHUI (CN)
ZHU JIN (CN)
JIANG LUBIN (CN)
WANG MANJIONG (CN)
LI RUOXI (CN)
TANG TONGKE (CN)
LING DAZHENG (CN)
HUANG ZHENGHUI (CN)
ZHU JIN (CN)
Application Number:
PCT/CN2019/077356
Publication Date:
September 10, 2020
Filing Date:
March 07, 2019
Export Citation:
Assignee:
UNIV EAST CHINA SCIENCE & TECH (CN)
INST PASTEUR SHANGHAI CAS (CN)
INST PASTEUR SHANGHAI CAS (CN)
International Classes:
C07D403/14; A61K31/506; A61P33/06
Domestic Patent References:
| WO2014026467A1 | 2014-02-20 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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