Title:
3-ANILINO-2-CYCLOALKENONE DERIVATES
Document Type and Number:
WIPO Patent Application WO/1998/058901
Kind Code:
A1
Abstract:
3-anilino-2-cycloalkenone derivatives represented by general formula (I), optical isomers thereof, pharmaceutically acceptable salts thereof, or hydrates or solvates of these: wherein R¿1? represents optionally substituted C¿1-8? alkyl (excluding methyl), cycloalkyl, 3-tetrahydrofuryl, 2-indanyl, etc.; R¿2? represents C¿1-4? alkyl; R¿3? represents H, optionally substituted C¿1-5? alkyl, C¿3-7? cycloalkyl, etc.; R¿4? represents H, optionally substituted C¿1-5? alkyl, halogeno, etc.; R¿5?, R¿6?, R¿7? and R¿8? each independently represents H, optionally substituted C¿1-5? alkyl, etc.; and X represents -(CR¿11?R¿12?)¿n? - (where n is 0 to 2, and R¿11? and R¿12? each independently represents H, optionally substituted C¿1-5? alkyl, etc.) or -NR¿13?- (where R¿13? represents H or optionally substituted C¿1-5? alkyl).
Inventors:
INA SHINJI (JP)
YAMANA KENJIRO (JP)
NODA KYOJI (JP)
TAKAHAMA AKANE (JP)
AKIYAMA TOSHIHIKO (JP)
YAMANA KENJIRO (JP)
NODA KYOJI (JP)
TAKAHAMA AKANE (JP)
AKIYAMA TOSHIHIKO (JP)
Application Number:
PCT/JP1997/004857
Publication Date:
December 30, 1998
Filing Date:
December 25, 1997
Export Citation:
Assignee:
NIKKEN CHEMICALS CO LTD (JP)
INA SHINJI (JP)
YAMANA KENJIRO (JP)
NODA KYOJI (JP)
TAKAHAMA AKANE (JP)
AKIYAMA TOSHIHIKO (JP)
INA SHINJI (JP)
YAMANA KENJIRO (JP)
NODA KYOJI (JP)
TAKAHAMA AKANE (JP)
AKIYAMA TOSHIHIKO (JP)
International Classes:
C07C225/20; C07C225/22; C07D211/86; C07D213/38; C07D215/12; C07D295/116; C07D307/20; (IPC1-7): C07C225/20; C07D215/12; C07D213/38; A61K31/135; A61K31/44; A61K31/47
Foreign References:
JPS495944A | 1974-01-19 | |||
JPH06100510A | 1994-04-12 | |||
JPH06100509A | 1994-04-12 | |||
JPH06100444A | 1994-04-12 | |||
JPH0597783A | 1993-04-20 | |||
JPH0551317A | 1993-03-02 |
Other References:
See also references of EP 0994100A4
Attorney, Agent or Firm:
Ishida, Takashi (Toramomon 37 Mori Building 5-1, Toranomon 3-chom, Minato-ku Tokyo 105, JP)
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