Title:
3-DIMENSIONAL CELL SHEET FOR WOUND OR ULCER TREATMENT AND METHOD OF PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2017/217803
Kind Code:
A1
Abstract:
The present invention relates to a 3-dimensional cell sheet for wound or ulcer treatment, and to a method of producing same. The cell sheet of the present invention can be produced without mouse-derived nutritional cells, special equipment, and special scaffolds. The cell sheet can be very easily detached from a culture medium through a simple physical method even without using a cell separator, and transplantation can be performed irrespective of the shape and size of a defective part. Accordingly, the cell sheet of the present invention can be usefully used for treating a mucosal defect, an ulcer, and the like after an operation of the oral cavity, the pharynx, the esophagus, or the like requiring re-epithelialization.
Inventors:
ROH JONG-LYEL (KR)
Application Number:
PCT/KR2017/006312
Publication Date:
December 21, 2017
Filing Date:
June 16, 2017
Export Citation:
Assignee:
UNIV ULSAN FOUND IND COOP (KR)
ASAN FOUND (KR)
ASAN FOUND (KR)
International Classes:
A61K9/70; A61K35/36; A61L15/14; A61L17/00; C12N5/071
Foreign References:
| US20130195958A1 | 2013-08-01 | |||
| JP2004147585A | 2004-05-27 | |||
| KR20160007901A | 2016-01-21 | |||
| US20030170892A1 | 2003-09-11 | |||
| KR20110032381A | 2011-03-30 |
Other References:
PENA, I. ET AL.: "In Vitro Engineering of Complete Autologous Oral Mucosa Equivalents: Characterization of a Novel Scaffold", JOURNAL OF PERIODONTAL RESEARCH, vol. 45, no. 3, 2010, pages 375 - 380, XP055448626
ROH, J. L. ET AL.: "Promotion of Oral Surgical Wound Healing Using Autologous Mucosal Cell Sheets", ORAL ONCOLOGY, vol. 69, 25 April 2017 (2017-04-25), pages 84 - 91, XP085044958
ROH, J. L. ET AL.: "Promotion of Oral Surgical Wound Healing Using Autologous Mucosal Cell Sheets", ORAL ONCOLOGY, vol. 69, 25 April 2017 (2017-04-25), pages 84 - 91, XP085044958
Attorney, Agent or Firm:
WIE, Byoung-Gap (KR)
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