Title:
3-`HYDROXY-(-4-TRIFLUOROMETHYLPHENYL)-METHYL-7-SPIROCYCLOBUTYL-5,6,7,8-TETRAHYDROQUINOLIN-5-OL DERIVATIVES AND THE USE OF THE SAME AS CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) INHIBITORS
Document Type and Number:
WIPO Patent Application WO2003028727
Kind Code:
A9
Abstract:
The invention relates to substituted tetrahydroquinoline derivatives of formula (I), wherein A represents a radical (a), (b), (c), (d), (e), (f), (g), (h) or -(CH2)2CH3 and B represents a radical (f) or (h), and to the salts of the same. The invention also relates to a method for producing said substances and to the use thereof in pharmaceuticals.
Inventors:
GIELEN HEIKE (DE)
GOLDMANN SIEGFRIED (DE)
KELDENICH JOERG (DE)
PAULSEN HOLGER (DE)
SCHMECK CARSTEN (DE)
SIEGEL STEPHAN (DE)
BISCHOFF HILMAR (DE)
RAABE MARTIN (DE)
SCHMIDT DELF (DE)
FAESTE CHRISTIANE (DE)
GOLDMANN SIEGFRIED (DE)
KELDENICH JOERG (DE)
PAULSEN HOLGER (DE)
SCHMECK CARSTEN (DE)
SIEGEL STEPHAN (DE)
BISCHOFF HILMAR (DE)
RAABE MARTIN (DE)
SCHMIDT DELF (DE)
FAESTE CHRISTIANE (DE)
Application Number:
PCT/EP2002/010444
Publication Date:
November 13, 2003
Filing Date:
September 18, 2002
Export Citation:
Assignee:
BAYER AG (DE)
GIELEN HEIKE (DE)
GOLDMANN SIEGFRIED (DE)
KELDENICH JOERG (DE)
PAULSEN HOLGER (DE)
SCHMECK CARSTEN (DE)
SIEGEL STEPHAN (DE)
BISCHOFF HILMAR (DE)
RAABE MARTIN (DE)
SCHMIDT DELF (DE)
FAESTE CHRISTIANE (DE)
GIELEN HEIKE (DE)
GOLDMANN SIEGFRIED (DE)
KELDENICH JOERG (DE)
PAULSEN HOLGER (DE)
SCHMECK CARSTEN (DE)
SIEGEL STEPHAN (DE)
BISCHOFF HILMAR (DE)
RAABE MARTIN (DE)
SCHMIDT DELF (DE)
FAESTE CHRISTIANE (DE)
International Classes:
A61K31/47; A61K31/4709; A61P3/04; C07D215/20; A61P3/06; A61P9/00; A61P9/10; A61P25/28; A61P43/00; C07D221/20; C07D409/04; (IPC1-7): A61K31/4747; C07D221/20; C07D409/04
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