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Title:
(3AS,4S,4AR,7AS,8S,8AS)-6-(4-ACETYL-PHENYL)-3-METHYL-4,4A,8,8A TETRAHYDRO- 3AH-4,8-METHANOISOXAZOLO [4,5-F]ISOINDOL-5,7(6H,7AH)-DIONE COMPOUND HAVING ANTI-CANCEROGENIC EFFICIENCY
Document Type and Number:
WIPO Patent Application WO/2018/231172
Kind Code:
A3
Abstract:
The present invention relates to (3aS,4S,4aR,7aS,8S,8aS)-6-(4-acetyl-phenyl)-3-methyl- 4, 4a, 8, 8a tetrahydro-3aH-4,8-methanoisoxazolo [4,5-f]isoindol-5,7(6H,7aH)-dione molecule shown by formula (1), the preparation method of this molecule, the formulations comprising this molecule and the usage of these molecules in treatment of cancer.

Inventors:
BUDAK, Yakup (Gaziosmanpasa Univ. Bilimsel Arastirma Projeleri Komisyon Baskanligi Tasciflik Kampus, Tokat, TR)
CEYLAN, Mustafa (Gaziosmanpasa Univ. Bilimsel Arastirma Projeleri Komisyon Baskanligi Tasciflik Kampus, Tokat, TR)
GURDERE, M. Burcu (Gaziosmanpasa Univ. Bilimsel Arastirma Projeleri Komisyon Baskanligi Tasciflik Kampus, Tokat, TR)
Application Number:
TR2017/050522
Publication Date:
March 14, 2019
Filing Date:
October 25, 2017
Export Citation:
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Assignee:
BUDAK, Yakup (Gaziosmanpasa Univ. Bilimsel Arastirma Projeleri Komisyon Baskanligi Tasciflik Kampus, Tokat, TR)
CEYLAN, Mustafa (Gaziosmanpasa Univ. Bilimsel Arastirma Projeleri Komisyon Baskanligi Tasciflik Kampus, Tokat, TR)
GURDERE, M. Burcu (Gaziosmanpasa Univ. Bilimsel Arastirma Projeleri Komisyon Baskanligi Tasciflik Kampus, Tokat, TR)
International Classes:
A61P35/04; A61K9/00; A61K31/12; A61K31/40
Other References:
CEYLAN, M: "Synthesis , characterization and biological activities of novel chalcone derivatives, containing 4, 7-ethanoisoindole-1, 3-dione units", ORGANIC COMMUNICATIONS, vol. 6, no. 3, 25 September 2013 (2013-09-25), pages 102 - 109, XP055581111
SHASTRI R.A.: "Review on Synthesis of 3-Substituted 1,2-Benzisoxazole Derivatives", CHEMICAL SCIENCE TRANSACTIONS, vol. 5, no. 1, 1 January 2016 (2016-01-01), pages 8 - 20, XP055581116, DOI: 10.7598/cst2016.1120
KARTHIKEYAN, C.: "Advances in chalcones with anticancer activities.", RECENT PAT ANTICANCER DRUG DISCOV., vol. 10, no. 1, 2015, pages 97 - 115, XP055581137, DOI: 10.2174/1574892809666140819153902
Attorney, Agent or Firm:
KAYA, Erdem (Konak Mh. Kudret Sok. Senyurt Is. Mrk. No:6 D:8-9, Nilufer/Bursa, 16110, TR)
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