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Title:
3D PRINTED ARTIFICIAL ENDOMETRIUM AND PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/029084
Kind Code:
A1
Abstract:
Provided is an artificial endometrium and a preparation method and application thereof. The artificial endometrium comprises a biocompatible stent, endometrial stromal cells/epithelial cells, and a mixed culture. With a 3D bioprinting technology, the biocompatible stent and the endometrial stromal cells/epithelial cells are made into a bioactive artificial endometrium. The artificial endometrium can be used as a tool for studying the pathophysiological mechanism of artificial endometrial diseases, a model for screening factors that regulate and influence the embryo implantation process, and a research tool for preventing or treating direct or indirect related diseases of endometrial lesions caused by any factor.

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Inventors:
ZHANG JIAN (CN)
RUAN CHANGSHUN (CN)
ZHAO HUASHAN (CN)
REN PEIGEN (CN)
YANG YALI (CN)
SUN LIFENG (CN)
ZHAI XINYUN (CN)
WU MINGMING (CN)
Application Number:
PCT/CN2017/116596
Publication Date:
February 14, 2019
Filing Date:
December 15, 2017
Export Citation:
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Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
C12N5/071
Domestic Patent References:
WO2016123362A12016-08-04
Foreign References:
CN104769101A2015-07-08
CN106139251A2016-11-23
CN105039245A2015-11-11
CN1416909A2003-05-14
Attorney, Agent or Firm:
BEIJING CHENGHUI LAW FIRM (CN)
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