Title:
4-AMINO-1,3-THIAZINE OR OXAZINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2011/077726
Kind Code:
A1
Abstract:
Disclosed is a compound represented by formula (1) (wherein X, R1, R2a, R2b, R3a, R3b, R4a, R4b, ring A, Y, and the dashed line are described in the description), a pharmaceutically acceptable salt thereof, or a solvate of either, as an agent for the treatment or prevention of diseases induced by the production, secretion and/or deposition of amyloid β proteins.
Inventors:
SUZUKI SHINJI (JP)
KOORIYAMA YUUJI (JP)
KOORIYAMA YUUJI (JP)
Application Number:
PCT/JP2010/007449
Publication Date:
June 30, 2011
Filing Date:
December 22, 2010
Export Citation:
Assignee:
SHIONOGI & CO (JP)
SUZUKI SHINJI (JP)
KOORIYAMA YUUJI (JP)
SUZUKI SHINJI (JP)
KOORIYAMA YUUJI (JP)
International Classes:
A61K31/536; C07D265/20; A61K31/54; A61K31/541; A61K31/5415; A61P25/28; A61P43/00; C07D279/06; C07D413/12; C07D417/12
Domestic Patent References:
| WO1997014686A1 | 1997-04-24 | |||
| WO2007058583A2 | 2007-05-24 | |||
| WO2007049532A1 | 2007-05-03 | |||
| WO2008133273A1 | 2008-11-06 | |||
| WO2007058583A2 | 2007-05-24 | |||
| WO2007004953A1 | 2007-01-11 | |||
| WO2008133273A1 | 2008-11-06 | |||
| WO2008133274A1 | 2008-11-06 | |||
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Foreign References:
| US20100261727A1 | 2010-10-14 | |||
| US5328915A | 1994-07-12 |
Other References:
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, vol. 37, no. 4, 2001, pages 522 - 523
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol. 36, no. 12, 2000, pages 1739 - 1742
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol. 33, no. 1, 1997, pages 96 - 102
JOURNAL OF ORGANIC CHEMISTRY, vol. 48, no. 4, 1983, pages 623 - 625
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 3, 2010, pages 1269 - 1271
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 7, 2010, pages 2279 - 2282
THE PREPARATION AND CHARACTERIZATION OF TRITIATED NEUROCHEMICALS, pages 155 - 192
"Isotopes in the Physical and Biomedical Sciences", LABELED COMPOUNDS (PART A, vol. 1, 1987
THEODORA W GREENE: "Protective Groups in organic Synthesis", JOHN WILEY & SONS
THEODORA W GREEN: "Protective Groups in Organic Synthesis", JOHN WILEY & SONS
TETRAHEDRON, vol. 65, 2009, pages 757 - 764
See also references of EP 2518059A4
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol. 36, no. 12, 2000, pages 1739 - 1742
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol. 33, no. 1, 1997, pages 96 - 102
JOURNAL OF ORGANIC CHEMISTRY, vol. 48, no. 4, 1983, pages 623 - 625
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 3, 2010, pages 1269 - 1271
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 7, 2010, pages 2279 - 2282
THE PREPARATION AND CHARACTERIZATION OF TRITIATED NEUROCHEMICALS, pages 155 - 192
"Isotopes in the Physical and Biomedical Sciences", LABELED COMPOUNDS (PART A, vol. 1, 1987
THEODORA W GREENE: "Protective Groups in organic Synthesis", JOHN WILEY & SONS
THEODORA W GREEN: "Protective Groups in Organic Synthesis", JOHN WILEY & SONS
TETRAHEDRON, vol. 65, 2009, pages 757 - 764
See also references of EP 2518059A4
Attorney, Agent or Firm:
YAMAMOTO, Shusaku et al. (JP)
Shusaku Yamamoto (JP)
Shusaku Yamamoto (JP)
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