Title:
4-AMINO-2H-PYRAN-2-ONE ANALOGS AS ANTICANCER AGENTS
Document Type and Number:
WIPO Patent Application WO/2012/061012
Kind Code:
A3
Abstract:
Compounds of Formula I are described, along with methods of using such compounds for the treatment of cancer and pharmaceutical formulations thereof.
Inventors:
LEE KUO-HSIUNG (US)
DONG YIZHOU (US)
BASTOW KENNETH F (US)
LEE EVA Y-H P (US)
NAKAGAWA-GOTO KYOKO (US)
DONG YIZHOU (US)
BASTOW KENNETH F (US)
LEE EVA Y-H P (US)
NAKAGAWA-GOTO KYOKO (US)
Application Number:
PCT/US2011/056801
Publication Date:
July 26, 2012
Filing Date:
October 19, 2011
Export Citation:
Assignee:
UNIV NORTH CAROLINA (US)
UNIV CALIFORNIA IRVINE (US)
LEE KUO-HSIUNG (US)
DONG YIZHOU (US)
BASTOW KENNETH F (US)
LEE EVA Y-H P (US)
NAKAGAWA-GOTO KYOKO (US)
UNIV CALIFORNIA IRVINE (US)
LEE KUO-HSIUNG (US)
DONG YIZHOU (US)
BASTOW KENNETH F (US)
LEE EVA Y-H P (US)
NAKAGAWA-GOTO KYOKO (US)
International Classes:
C07D309/38; A61K31/351; A61K31/366; A61P35/00; C07D405/04; C07D407/04
Domestic Patent References:
| WO2010080415A2 | 2010-07-15 |
Foreign References:
| US20020010204A1 | 2002-01-24 | |||
| US20080161582A1 | 2008-07-03 |
Other References:
IKURO ABE ET AL.: "Enzymatic formation of unnatural novel polyketides from a lternate starter and nonphysiological extension substrate by chalcone synthase.", ORG. LETT., vol. 5, no. 8, 2003, pages 1277 - 1280
SIRISILLA RAJU ET AL.: "Tandem versus single C-C bond forming reaction under palladium-copper catalysis: regioselective synthesis of alpha-pyrones fused with thiophene.", TETRAHEDRON, vol. 62, 2006, pages 9554 - 9570
SIRISILLA RAJU ET AL.: "Tandem versus single C-C bond forming reaction under palladium-copper catalysis: regioselective synthesis of alpha-pyrones fused with thiophene.", TETRAHEDRON, vol. 62, 2006, pages 9554 - 9570
Attorney, Agent or Firm:
MYERS BIGEL SIBLEY & SAJOVEC, P.A. (Raleigh, North Carolina, US)
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