Title:
4-(SUBSTITUTED AMINOMETHYL)THIAZOLINE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1997/003059
Kind Code:
A1
Abstract:
Object: to provide compounds having an excellent antiplatelet aggregation effect and a good oral activity. Constitution: thiazoline derivatives represented by general formula (I) and salts thereof, wherein R1 represents (II) (wherein R11 and R12 represent each hydrogen, alkyl, alkoxy-carbonyl, cycloalkyl, optionally substituted phenyl or optionally substituted aralkyl), imidazolin-2-yl, etc; R2 represents (III) (wherein R41 and R42 represent each hydrogen, alkyl, cycloalkyl, optionally substituted phenyl or optionally substituted aralkyl), etc.; R3 represents hydrogen or alkyl); and R4 represents alkyl.
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Inventors:
SATO MASAKAZU (JP)
MANAKA AKIRA (JP)
TAKAHASHI KEIKO (JP)
KAWASHIMA YUTAKA (JP)
HATAYAMA KATSUO (JP)
MANAKA AKIRA (JP)
TAKAHASHI KEIKO (JP)
KAWASHIMA YUTAKA (JP)
HATAYAMA KATSUO (JP)
Application Number:
PCT/JP1996/001923
Publication Date:
January 30, 1997
Filing Date:
July 11, 1996
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
SATO MASAKAZU (JP)
MANAKA AKIRA (JP)
TAKAHASHI KEIKO (JP)
KAWASHIMA YUTAKA (JP)
HATAYAMA KATSUO (JP)
SATO MASAKAZU (JP)
MANAKA AKIRA (JP)
TAKAHASHI KEIKO (JP)
KAWASHIMA YUTAKA (JP)
HATAYAMA KATSUO (JP)
International Classes:
C07D277/56; (IPC1-7): C07D277/56; C07D417/06; C07D417/12; C07D417/14
Domestic Patent References:
| WO1994002472A1 | 1994-02-03 |
Foreign References:
| JPH08119953A | 1996-05-14 | |||
| JPH0859641A | 1996-03-05 | |||
| JPH07242646A | 1995-09-19 |
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