Title:
4-SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/045598
Kind Code:
A1
Abstract:
Provided are a 4-substituted pyrrolo[2,3-d]pyrimidine compound and the use thereof in preparing medicaments for treating JAK-targeted diseases, such as rheumatoid, immune system diseases, tumours, etc. The 4-substituted pyrrolo[2,3-d]pyrimidine compound is as shown in the structural formula (I). The activity results show that some of compounds as shown in formula (I) have a strong inhibiting effect on Janus kinases.
Inventors:
QIN YINLIN (CN)
SU MEI (CN)
JIN QIU (CN)
CHEN TAO (CN)
WU XIANZHI (CN)
JIANG JIANHUA (CN)
SU MEI (CN)
JIN QIU (CN)
CHEN TAO (CN)
WU XIANZHI (CN)
JIANG JIANHUA (CN)
Application Number:
PCT/CN2015/090497
Publication Date:
March 31, 2016
Filing Date:
September 24, 2015
Export Citation:
Assignee:
JIANGSU CAREPHAR PHARMACEUTICAL CO LTD (CN)
NANJING CAREPHAR SHENGHUI PHARMACEUTICAL CO LTD (CN)
NANJING CAREPHAR PHARMACEUTICAL CO LTD (CN)
NANJING CAREPHAR SHENGHUI PHARMACEUTICAL CO LTD (CN)
NANJING CAREPHAR PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D487/04; A61K31/395; A61K31/437; A61K31/4375; A61P29/00; A61P35/00; A61P37/00
Foreign References:
| CN101448826A | 2009-06-03 | |||
| CN101142218A | 2008-03-12 | |||
| CN1305479A | 2001-07-25 | |||
| CN102026999A | 2011-04-20 |
Attorney, Agent or Firm:
JIANGSU CO-FAR LAW FIRM (CN)
江苏致邦律师事务所 (CN)
江苏致邦律师事务所 (CN)
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