Title:
5-FLUORO-7H-PYRROLO[2,3-D] PYRIMIDINES COMPOUND AS WEE-1 INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2023/030388
Kind Code:
A1
Abstract:
Disclosed is a 5-fluoro-7H-pyrrolo[2,3-d] pyrimidines compound as a Wee-1 inhibitor, in particular, relating to a compound represented by general formula (I) and a preparation method therefor, and use of the compound represented by general formula (I) and isomers, crystal forms, a pharmaceutically acceptable salt, a hydrate or a solvate thereof as a Wee-1 inhibitor. The compound and the isomers, the crystal forms, the pharmaceutically acceptable salt, the hydrate or the solvate thereof can be used for preparing drugs for treating or preventing diseases associated with a Wee-1 protein kinase.
Inventors:
XIE YULI (CN)
WU YINGMING (CN)
QIAN LIHUI (CN)
WU YINGMING (CN)
QIAN LIHUI (CN)
Application Number:
PCT/CN2022/116219
Publication Date:
March 09, 2023
Filing Date:
August 31, 2022
Export Citation:
Assignee:
WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN)
International Classes:
C07D487/04; A61K31/519; A61P35/00
Domestic Patent References:
| WO2005107760A1 | 2005-11-17 | |||
| WO2021074251A1 | 2021-04-22 |
Foreign References:
| CN1918158A | 2007-02-21 | |||
| CN111718348A | 2020-09-29 | |||
| CN112724144A | 2021-04-30 | |||
| CN110467615A | 2019-11-19 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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