5-SUBSTITUTED-2-PHENYLAMINO-BENZAMIDE AS MEK INHIBITOR

Title:

5-SUBSTITUTED-2-PHENYLAMINO-BENZAMIDE AS MEK INHIBITOR

Document Type and Number:

WIPO Patent Application WO/2006/011466

Kind Code:

A1

Abstract:

Disclosed are a compound and pharmaceutically acceptable salts thereof represented by the general formula (1) below. (In the formula (1), R₁, R₂, R₃, R₄ and X are the same as R₁, R₂, R₃, R₄ and X defined in the description.)

Inventors:

ISSHIKI YOSHIAKI (JP)
KOHCHI YASUNORI (JP)
MIZUGUCHI EISAKU (JP)
IIKURA HITOSHI (JP)
MATSUBARA YASUAKI (JP)
TSUJII SHINJI (JP)
SHIMMA NOBUO (JP)
MIWA MASANORI (JP)
AIDA SATOSHI (JP)
KOHCHI MASAMI (JP)
MURATA TAKESHI (JP)
ASO KOSUKE (JP)

Application Number:

PCT/JP2005/013620

Publication Date:

February 02, 2006

Filing Date:

July 26, 2005

Export Citation:

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Assignee:

CHUGAI PHARMACEUTICAL CO LTD (JP)
ISSHIKI YOSHIAKI (JP)
KOHCHI YASUNORI (JP)
MIZUGUCHI EISAKU (JP)
IIKURA HITOSHI (JP)
MATSUBARA YASUAKI (JP)
TSUJII SHINJI (JP)
SHIMMA NOBUO (JP)
MIWA MASANORI (JP)
AIDA SATOSHI (JP)
KOHCHI MASAMI (JP)
MURATA TAKESHI (JP)
ASO KOSUKE (JP)

International Classes:

C07C259/10; A61K31/166; A61K31/4015; A61K31/4164; A61K31/42; A61K31/421; A61K31/45; A61K31/505; A61K31/535; A61K31/5375; A61K31/539; A61P1/16; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P17/06; A61P19/02; A61P25/28; A61P29/00; A61P31/04; A61P31/18; A61P37/00; A61P37/06; A61P43/00; C07C11/24; C07C317/04; C07C323/12; C07D207/27; C07D211/76; C07D233/64; C07D239/10; C07D261/04; C07D263/24; C07D265/02; C07D265/32; C07D273/01; C07D295/08

Domestic Patent References:

WO2005028426A1

2005-03-31

Foreign References:

JP2003527379A

2003-09-16

Other References: