Title:
"6-ARYL-4-PHENYLAMINO-QUINAZOLINE ANALOGS AS PHOSPHOINOSITIDE-3-KINASE INHIBITORS"
Document Type and Number:
WIPO Patent Application WO/2015/128873
Kind Code:
A9
Abstract:
The present invention relates to 6-aryl-4-phenylamino quinazolines of formula I wherein, R and R´ are as herein described. The present invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-α (PI3K-α ) inhibitory activity. In addition, the invention relates to methods of using compounds for treating or preventing various cancers such as pancreatic, prostate, breast and melanoma.
Inventors:
VISHWAKARMA RAM ASREY (IN)
BHARATE SANDIP BIBISHAN (IN)
BHUSHAN SHASHI (IN)
YADAV RAMMOHAN RAO (IN)
GURU SANTOSH KUMAR (IN)
JOSHI PRASHANT (IN)
BHARATE SANDIP BIBISHAN (IN)
BHUSHAN SHASHI (IN)
YADAV RAMMOHAN RAO (IN)
GURU SANTOSH KUMAR (IN)
JOSHI PRASHANT (IN)
Application Number:
PCT/IN2015/000088
Publication Date:
December 03, 2015
Filing Date:
February 16, 2015
Export Citation:
Assignee:
COUNCIL SCIENT IND RES (IN)
International Classes:
C07D401/04; A61K31/517; A61P35/00; C07D239/94; C07D403/04; C07D405/04; C07D409/04
Attorney, Agent or Firm:
CHOPRA, Priyanka et al. (Intellectual Property Attorneys109, Sector 4, Gurgaon National Capital Region 3, IN)
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