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Title:
7-PHENYL-SUBSTITUTED TETRACYCLINE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2001098236
Kind Code:
A3
Abstract:
7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. 7-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described.

Inventors:
NELSON MARK
ISMAIL MOHAMED Y
Application Number:
US0119286W
Publication Date:
March 28, 2002
Filing Date:
June 15, 2001
Export Citation:
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Assignee:
TUFTS COLLEGE (US)
International Classes:
A61K31/65; C07C237/26; (IPC1-7): C07C237/26; A61K31/65; A61P31/04; C07C231/12
Domestic Patent References:
WO2001019784A12001-03-22
Foreign References:
FR2208885A11974-06-28
Other References:
KOZA D J: "SYNTHESIS OF 7-SUBSTITUTED TETRACYCLINE DERIVATIVES", ORGANIC LETTERS, ACS, WASHINGTON, DC, US, vol. 2, no. 6, 2000, pages 815 - 817, XP000943852, ISSN: 1523-7060
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