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Title:
9-SUBSTITUTED MINOCYCLINE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2002004406
Kind Code:
A3
Abstract:
The present invention pertains, at least in part, to novel 9- substituted minocycline compounds. These minocyline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

Inventors:
NELSON MARK L
FRECHETTE ROGER
VISKI PETER
ISMAIL MOHAMED
BOWSER TODD
DUMORNAY JIMMY
RENNIE GLEN
LIU GUI
KOZA DARRELL
SHEAHAN PAUL
STAPLETON KAREN
HAWKINS PAUL
BHATIA BEENA
VERMA ATUL
MCINTYRE LAURA
WARCHOL TAD
Application Number:
PCT/US2001/020721
Publication Date:
June 06, 2002
Filing Date:
June 29, 2001
Export Citation:
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Assignee:
TUFTS COLLEGE (US)
PARATEK PHARACEUTICALS INC (US)
International Classes:
A61K31/65; C07D317/58; A61P31/04; C07C237/00; C07C237/26; C07C255/59; C07C271/22; C07C271/28; C07C271/30; C07C271/58; C07C275/30; C07C275/34; C07C275/38; C07C275/40; C07C275/42; C07C275/50; C07C275/54; C07C279/18; C07C311/06; C07C311/13; C07C311/21; C07C331/24; C07C333/08; C07C335/22; C07C381/10; C07D295/155; C07D317/62; C07F9/40; A61K; C07C; (IPC1-7): C07C237/26; A61K31/65
Domestic Patent References:
WO2001074761A12001-10-11
WO2001019784A12001-03-22
Foreign References:
EP0582810A11994-02-16
EP0536515A11993-04-14
EP0535346A11993-04-07
EP0582790A11994-02-16
FR2208885A11974-06-28
US3338963A1967-08-29
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