Title:
AMP DEAMINASE ORIGINATING IN STREPTOMYCES AND UTILIZATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2005/105991
Kind Code:
A1
Abstract:
It is intended to provide a thermostable AMP deaminase originating in a microorganism. Namely, an AMP deaminase having the following characteristics. (1) Catalyzing the reaction 5’-adenylic acid + H2O → 5’-inosinic acid + NH3; (2) being stable at a temperature of 65oC or below (in an acetate buffer (pH 5.6)); (3) having a molecular weight of 48,000 ± 2,000 in gel filtration; and (4) having the optimum pH value at around 5.6 (in Mcllvaine buffer).
Inventors:
YAMASHITA RYOKO (JP)
MORI SHIGEHARU (JP)
TOUMOTO ATSUKI (JP)
ANDO KEI-ICHI (JP)
YUUKI KENSUKE (JP)
MORI SHIGEHARU (JP)
TOUMOTO ATSUKI (JP)
ANDO KEI-ICHI (JP)
YUUKI KENSUKE (JP)
Application Number:
PCT/JP2005/007892
Publication Date:
November 10, 2005
Filing Date:
April 26, 2005
Export Citation:
Assignee:
AMANO ENZYME INC (JP)
YAMASHITA RYOKO (JP)
MORI SHIGEHARU (JP)
TOUMOTO ATSUKI (JP)
ANDO KEI-ICHI (JP)
YUUKI KENSUKE (JP)
YAMASHITA RYOKO (JP)
MORI SHIGEHARU (JP)
TOUMOTO ATSUKI (JP)
ANDO KEI-ICHI (JP)
YUUKI KENSUKE (JP)
International Classes:
A23L27/10; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/78; C12N15/31; C12P1/00; C12P19/32; (IPC1-7): C12N9/78; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/31; C12P1/00; C12P19/32
Foreign References:
| JPS55120788A | 1980-09-17 | |||
| JPS5022115B1 | 1975-07-28 | |||
| JPH06113789A | 1994-04-26 | |||
| JPH0670716A | 1994-03-15 | |||
| JPH04131084A | 1992-05-01 |
Other References:
MARGOLIN A.L. ET AL: "AMP Deaminase as a Novel Practical Catalyst in the Synthesis of 6-Oxopurine Ribosides and Their Analogs.", J.ORG.CHEM., vol. 59, no. 24, 1994, pages 7214 - 7218, XP002988972
BANDLINSH R.K. ET AL: "Glucose-to-fructose conversion at high temperatures with xylose (glucose) isomerases from Streptomyces murinus and two hyperthermophilic Thermotoga species.", BIOTECHNOL BIOENG., vol. 80, no. 2, October 2002 (2002-10-01), pages 185 - 194, XP002988954
CHUNG S.T. ET AL: "A relationship between deamination and dechlorination activities of ATP Deaminase, ADP-deaminating enzyme and AMP Deaminase.", J GEN APPL MICROBIOL., vol. 14, 1986, pages 111 - 119, XP002987384
See also references of EP 1760148A4
BANDLINSH R.K. ET AL: "Glucose-to-fructose conversion at high temperatures with xylose (glucose) isomerases from Streptomyces murinus and two hyperthermophilic Thermotoga species.", BIOTECHNOL BIOENG., vol. 80, no. 2, October 2002 (2002-10-01), pages 185 - 194, XP002988954
CHUNG S.T. ET AL: "A relationship between deamination and dechlorination activities of ATP Deaminase, ADP-deaminating enzyme and AMP Deaminase.", J GEN APPL MICROBIOL., vol. 14, 1986, pages 111 - 119, XP002987384
See also references of EP 1760148A4
Attorney, Agent or Firm:
Konishi, Tomimasa (17-12 Marunouchi 2-chome, Naka-k, Nagoya-shi Aichi 02, JP)
Download PDF: