AAV DELIVERY OF SHRNA FOR TREATMENT OF PANCREATIC CANCER

Title:

AAV DELIVERY OF SHRNA FOR TREATMENT OF PANCREATIC CANCER

Document Type and Number:

WIPO Patent Application WO/2018/132155

Kind Code:

A3

Abstract:

Aspects of the disclosure relate to methods and compositions for treating pancreatic cancer (e.g., islet cell tumors). In some aspects, adeno-associated virus (AAV) may be used to deliver an interfering RNA that targets thymidylate synthase (TS).

Inventors:

ZAJAC-KAYE MARIA (US)
MAENG KYUNGAH (US)

Application Number:

PCT/US2017/059843

Publication Date:

October 18, 2018

Filing Date:

November 03, 2017

Export Citation:

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Assignee:

UNIV FLORIDA (US)

International Classes:

A61K31/513; A61K31/7072; A61K38/00; A61K48/00; C07H21/04; C12Q1/68

Foreign References:

US20090258925A1	2009-10-15
US20070015238A1	2007-01-18
US20060089322A1	2006-04-27
US20160151371A1	2016-06-02
US20130276169A1	2013-10-17

Attorney, Agent or Firm:

MCMAHON, Amy, J. et al. (US)

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