Title:
AAV VECTORS TARGETING T-CELLS
Document Type and Number:
WIPO Patent Application WO/2022/155482
Kind Code:
A9
Abstract:
The disclosure provides variant AAV capsid proteins and AAV capsids and virus vectors comprising the same. The virus vectors described herein may have increased transduction in a target cell of interest, such as a T-cell, compared to native AAV capsid sequences. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a patient in need thereof.
Inventors:
SMITH JAMES KENNON (US)
Application Number:
PCT/US2022/012542
Publication Date:
December 22, 2022
Filing Date:
January 14, 2022
Export Citation:
Assignee:
STRIDEBIO INC (US)
International Classes:
C07K14/075; C12N15/861
Attorney, Agent or Firm:
TUSCAN, Michael S. et al. (US)
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