Title:
ACETOPHENONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN FATTY LIVER PREVENTION AND TREATMENT
Document Type and Number:
WIPO Patent Application WO/2018/166505
Kind Code:
A1
Abstract:
Disclosed are a compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method therefor, and an application thereof in preventing or treating fatty liver or in preparing weight-reducing drugs.
Inventors:
DONG YUQIONG (CN)
LIU QUANHAI (CN)
SHEN YU (CN)
CAI WENTAO (CN)
LIU QUANHAI (CN)
SHEN YU (CN)
CAI WENTAO (CN)
Application Number:
PCT/CN2018/079181
Publication Date:
September 20, 2018
Filing Date:
March 15, 2018
Export Citation:
Assignee:
SHANGHAI BIOENERGY MEDICINE SCIENCE & TECH CO LTD (CN)
International Classes:
C07D213/82; A61K31/166; A61K31/222; A61P3/04; C07C231/02; C07C235/20; C07C235/24; C07C235/26; C07C235/84; C07C251/16
Foreign References:
| CN106146335A | 2016-11-23 | |||
| CN103087009A | 2013-05-08 | |||
| CN104292120A | 2015-01-21 | |||
| CN102093246A | 2011-06-15 | |||
| CN102838505A | 2012-12-26 | |||
| CN101108173A | 2008-01-23 |
Other References:
DATABASE Registry [O] 11 August 2006 (2006-08-11), retrieved from STN Database accession no. 900748-86-9
DEHMEL, F. ET AL.: "Trithiocarbonates as a Novel Class of HDAC Inhibitors: SAR Studies , Isoenzyme Selectivity, and Pharmacological Profiles", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 13, 18 June 2008 (2008-06-18), pages 3985 - 4001, XP055131499, ISSN: 0022-2623
See also references of EP 3597638A4
DEHMEL, F. ET AL.: "Trithiocarbonates as a Novel Class of HDAC Inhibitors: SAR Studies , Isoenzyme Selectivity, and Pharmacological Profiles", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 13, 18 June 2008 (2008-06-18), pages 3985 - 4001, XP055131499, ISSN: 0022-2623
See also references of EP 3597638A4
Attorney, Agent or Firm:
JIAQUAN IP LAW FIRM (CN)
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