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Patent Searching and Data


Title:
ACID-RESISTANT YEAST WITH SUPRESSED ETHANOL PRODUCTION PATHWAY AND METHOD FOR PRODUCING LACTIC ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/203436
Kind Code:
A1
Abstract:
The present invention relates to an acid-resistant yeast endowed with a lactic acid production ability and having a suppressed ethanol production pathway, and a method for producing lactic acid using same. According to the present invention, by effectively suppressing the production of ethanol in an acid-resistant yeast, and by expressing an LDH enzyme with strong expression and high efficiency, it is possible to produce lactic acid with high yield even at low pH without degrading growth.

Inventors:
PARK JAE YEON (KR)
LEE TAE YOUNG (KR)
LEE KI SUNG (KR)
Application Number:
PCT/KR2019/002433
Publication Date:
October 24, 2019
Filing Date:
February 28, 2019
Export Citation:
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Assignee:
SK INNOVATION CO LTD (KR)
International Classes:
C12N15/81; C07K14/39; C12N9/04; C12P7/56
Foreign References:
US7049108B22006-05-23
KR20160133308A2016-11-22
JP2005137306A2005-06-02
KR20170025315A2017-03-08
KR20160012561A2016-02-03
US7534597B22009-05-19
US7141410B22006-11-28
US9353388B22016-05-31
JP4692173B22011-06-01
JP2001204464A2001-07-31
JP4095889B22008-06-04
KR101686900B12016-12-16
KR20170025315A2017-03-08
Other References:
ABBOTT, D. A.: "Metabolic engineering of Saccharomyces cerevisiae for production of carboxylic acids: current status and challenges", FEMS YEAST RESEARCH, pages 1123 - 1136, XP002557537
ELLEN I. GARVIE, MICROBIOLOGICAL REVIEWS, 1980, pages 106 - 139
MICHAEL SAUER ET AL., BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS, vol. 27, no. 1, 2010, pages 229 - 256
YIMING ZHANG ET AL., MICROBIAL CELL FACTORY, vol. 14, 2015, pages 116
N. ISHIDA, APPL. ENVIRON. MICROBIOL., 2005, pages 1964 - 1970
KENRO TOKUHIRO ET AL., APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 82, 2009, pages 883 - 890
See also references of EP 3795689A4
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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