Title:
ACTIVATABLE DEVICES CONTAINING A CHEMONUCLEOLYSIS AGENT
Document Type and Number:
WIPO Patent Application WO/2012/058297
Kind Code:
A3
Abstract:
Effective devices and methods using a chemonucleolysis agent are provided for treating an intervertebral disc or treating spinal arachnoiditis. The devices and methods comprise a chemonucleolysis agent to degrade or to shrink at least a portion of the intervertebral disc. In some embodiments, the methods and devices are configured to immediately release an effective amount of the chemonucleolysis agent within 24 hours when the device comes in contact directly or indirectly with an activator and provide sustained release of the chemonucleolysis agent over a period of up to one year to treat the intervertebral disc. In some embodiments, the chemonucleolysis agent in the device is administered in or near the intrathecal space and/or thecal sac to treat spinal arachnoiditis.
Inventors:
LEE ELAINE (US)
Application Number:
PCT/US2011/057868
Publication Date:
July 05, 2012
Filing Date:
October 26, 2011
Export Citation:
Assignee:
KYPHON SARL (CH)
LEE ELAINE (US)
LEE ELAINE (US)
International Classes:
A61F2/44; A61L27/14; A61L27/54; A61N2/00; A61N7/00
Foreign References:
| US7169405B2 | 2007-01-30 | |||
| US20050234425A1 | 2005-10-20 | |||
| US20080027554A1 | 2008-01-31 | |||
| US20030181964A1 | 2003-09-25 | |||
| US20070250044A1 | 2007-10-25 | |||
| US4719108A | 1988-01-12 |
Attorney, Agent or Firm:
PATEL, Samir R. (Inc.MS LC340,710 Medtronic Parkwa, Minneapolis Minnesota, US)
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