Title:
ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS
Document Type and Number:
WIPO Patent Application WO2005048944
Kind Code:
A3
Abstract:
The present invention relates to the field of conjugates comprising a first substrate which is attached to a least one photosensitizer and at least ont first quencher, and methods for their use. More particularly, the present invention relates to photodynamic therapy agents. The invention further relates to methods for decontaminating blood and methods for treating cancer or viral infection in a subject using the conjugates of the present invention.
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Inventors:
ZHENG GANG (US)
GLICKSON JERRY D (US)
CHANCE BRITTON (US)
DELIKATNY EDWARD JAMES (US)
GLICKSON JERRY D (US)
CHANCE BRITTON (US)
DELIKATNY EDWARD JAMES (US)
Application Number:
PCT/US2004/038024
Publication Date:
May 04, 2006
Filing Date:
November 15, 2004
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
ZHENG GANG (US)
GLICKSON JERRY D (US)
CHANCE BRITTON (US)
DELIKATNY EDWARD JAMES (US)
ZHENG GANG (US)
GLICKSON JERRY D (US)
CHANCE BRITTON (US)
DELIKATNY EDWARD JAMES (US)
International Classes:
A61K38/00; A61K38/02; A61K38/05; A61K38/06; A61K38/07; A61K38/08; A61K38/10; A61K38/16; A61K41/00; A61K47/48; C07K2/00; C07K5/10; C07K7/04; C07K7/08; C07K14/00; A61K
Foreign References:
| US6103751A | 2000-08-15 | |||
| US6159445A | 2000-12-12 | |||
| US6540981B2 | 2003-04-01 |
Other References:
MATAYOSHI E.D. ET AL: "Novel Fluorogenic Substrates for Assaying Retroviral Protease by Resonance Energy Transfer", SCIENCE, vol. 247, no. 4945, 23 February 1990 (1990-02-23), pages 954 - 958, XP002056345
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