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Title:
ACYL STERYL GLUCOSIDE, METHOD FOR PRODUCING ACYL STERYL GLUCOSIDE, COMPOSITION, ANTIOXIDANT, HAIR-GROWING OR HAIR-RESTORING AGENT, BLOOD LIPID LOWERING AGENT, ANTI-OBESITY AGENT, ANTITUMOR AGENT, AND PROPHYLACTIC OR THERAPEUTIC AGENT FOR ATHEROSCLEROSIS
Document Type and Number:
WIPO Patent Application WO/2019/106865
Kind Code:
A1
Abstract:
Provided are: an acyl novel steryl glucoside; and a method for producing an acyl steryl glucoside by using labyrinthula as a raw material. This acyl steryl glucoside is represented by structural formula (I), structural formula (II), or structural formula (III).

Inventors:
ITO, Makoto (NATIONAL UNIVERSITY CORPORATION 6-10-1, Hakozaki, Higashi-ku, Fukuoka-sh, Fukuoka 81, 〒8128581, JP)
WATANABE, Takashi (NATIONAL UNIVERSITY CORPORATION 6-10-1, Hakozaki, Higashi-ku, Fukuoka-sh, Fukuoka 81, 〒8128581, JP)
UEMURA, Suzumi (NATIONAL UNIVERSITY CORPORATION 6-10-1, Hakozaki, Higashi-ku, Fukuoka-sh, Fukuoka 81, 〒8128581, JP)
SUZUKI, Kengo (4F, Leading Venture Plaza 1, 75-1, Ono-cho, Tsurumi-ku, Yokohama-sh, Kanagawa 46, 〒2300046, JP)
SUGIMOTO, Ryota (4F, Leading Venture Plaza 1, 75-1, Ono-cho, Tsurumi-ku, Yokohama-sh, Kanagawa 46, 〒2300046, JP)
HAYASHI, Masahiro (1-1 Gakuen Kibanadai-nishi, Miyazaki-Sh, Miyazaki 92, 〒8892192, JP)
Application Number:
JP2018/021018
Publication Date:
June 06, 2019
Filing Date:
May 31, 2018
Export Citation:
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Assignee:
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (6-10-1, Hakozaki Higashi-ku, Fukuoka-sh, Fukuoka 81, 〒8128581, JP)
EUGLENA CO., LTD. (5-29-11 Shiba, Minato-ku Tokyo, 14, 〒1080014, JP)
International Classes:
C12P19/56; A23L31/00; A61K8/99; A61K31/704; A61K35/74; A61P3/04; A61P3/06; A61P9/10; A61P17/14; A61P35/00; A61P39/06; A61Q19/00; A61Q19/06; C07J9/00; C07J13/00; C12N1/14; C12P7/62; C12P19/44
Foreign References:
JPH0870885A1996-03-19
JPH07118159A1995-05-09
JPH07107939A1995-04-25
JP2009523414A2009-06-25
JPH07101835A1995-04-18
Other References:
WIMMEROVA MARTINA ET AL.: "Improved enzyme-mediated synthesis and supramolecular self-assembly of naturally occuring conjugates of beta- sitosterol", STEROIDS, vol. 117, 2016, pages 38 - 43, XP029858304
NHUNG BUI THI ET AL.: "Rice Bran Extract Reduces the Risk of Atherosclerosis in Post-Menopausal Vietnamese Women", J. NUTR. SCI. VITAMINOL., vol. 62, no. 5, 2016, pages 295 - 302, XP055615936
ENDO, IKUMI ET AL.: "Analysis for the disruption mutants of sterylglucoside synthase genes in thraustochytrids", ABSTRACTS OF THE 87TH ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY, 2014, pages 278 - 279
SETO, NORIKAZU ET AL.: "Analysis of long-chain base C9 methyltransferase-deficient mutants of thraustochytrids", ABSTRACTS OF THE 87TH ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY, 2014, pages 146
NUTAHARA, ERI ET AL.: "DHA-glycerolipids are synthesized via DHA-phosphatidic acid in thraustochytrids", ABSTRACTS OF THE 87TH ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY, 2014, pages 170
UEMURA, RYO ET AL.: "Identification of DHA containing acyl steryl glycosides in thraustochytrids", ABSTRACTS OF THE 19TH ANNUAL MEETING OF THE JAPANESE SOCIETY FOR MARINE BIOTECHNOLOGY, 3 June 2017 (2017-06-03), pages 94
Attorney, Agent or Firm:
AKIYAMA, Atsushi et al. (33F Ark Mori Building, 12-32 Akasaka 1-chome, Minato-k, Tokyo 33, 〒1076033, JP)
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