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Patent Searching and Data


Title:
ADDITIVELY MANUFACTURED FUNCTIONAL DOSAGE FORMS
Document Type and Number:
WIPO Patent Application WO/2019/025857
Kind Code:
A8
Abstract:
3D printed functional dosage forms, and methods for making thereof are disclosed. In one aspect of the disclosure, a dosage form is presented that includes an outer shell printed from a first material and at least one inner core containing an active pharmaceutical ingredient (API) disposed within the outer shell. The dosage form includes an opening structure extending from an outer surface of the outer shell to the at least one inner core. The dosage form may include a plurality of pH sensitive mucoadhesive projections printed from a third material and extending from the outer shell. The dosage form may include a plug printed from the second or third material within the opening structure and can include an outer cap printed over the plug from a fourth material. The dosage form also may include an internal hollow cavity such that the dosage form is buoyant in an aqueous solution.

Inventors:
NIE HAICHEN (US)
DRAGER ANTHONY (US)
WATTAMWAR PARITOSH (US)
MCINTYRE BRADLEY (US)
YAZDANIAN SR MEHAN (US)
Application Number:
PCT/IB2018/000974
Publication Date:
June 13, 2019
Filing Date:
July 30, 2018
Export Citation:
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Assignee:
TEVA PHARMACEUTICALS INDUSTRIES LTD (IL)
International Classes:
A61K9/48; B29C64/118; B29C64/336
Attorney, Agent or Firm:
KORAKH, Eliav (IL)
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