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Patent Searching and Data


Title:
ADHESION PREVENTION MATERIAL
Document Type and Number:
WIPO Patent Application WO/2019/078349
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an adhesion prevention material capable of exhibiting excellent adhesion preventive effect. This adhesion prevention material concurrently uses: (A) a peptide (A-1) having an amino acid sequence ―(X―Pro―Y)n― [wherein X represents an arbitrary defined amino acid, Pro represents proline, Y represents hydroxyproline or proline, and n is an integer between 1 and 10] and/or a peptide (A-2) having an amino acid sequence ―(Pro―Y)m― [wherein Pro represents proline, Y represents hydroxyproline or proline, and m is an integer between 1-10]; and (B) a gelatin gel. This adhesion prevention material exhibits a dramatically enhanced adhesion preventive effect as compared with the case where the abovementioned components are used individually, and in particular, has a markedly superior effect against adhesion of tendons.

Inventors:
FUJII, Namiki (Inc. 115 AzaKuguhara, Tateiwa, Muya-cho, Naruto-sh, Tokushima 01, 〒7728601, JP)
YOSHIOKA, Yuichiro (Inc. 115 AzaKuguhara, Tateiwa, Muya-cho, Naruto-sh, Tokushima 01, 〒7728601, JP)
FUKUDA, Tatsuru (Inc. 115 AzaKuguhara, Tateiwa, Muya-cho, Naruto-sh, Tokushima 01, 〒7728601, JP)
Application Number:
JP2018/038977
Publication Date:
April 25, 2019
Filing Date:
October 19, 2018
Export Citation:
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Assignee:
OTSUKA PHARMACEUTICAL FACTORY, INC. (115 AzaKuguhara, Tateiwa Muya-cho, Naruto-sh, Tokushima 01, 〒7728601, JP)
International Classes:
A61L31/06; A61L31/04; A61L31/14; C07K5/078; C07K5/08; C07K5/083; C07K14/78
Domestic Patent References:
WO1998022157A11998-05-28
Foreign References:
JP2000271207A2000-10-03
JPH10113384A1998-05-06
JP2013223644A2013-10-31
JPH08500334A1996-01-16
JPH0852204A1996-02-27
JP2004065780A2004-03-04
JP2013112653A2013-06-10
Other References:
ALBERTS, B. ET AL.: "Molecular Biology of the Cell", 5EM EDITION- 3RD PRINT, 20 October 2011 (2011-10-20), pages 1184 - 1185, Retrieved from the Internet
Attorney, Agent or Firm:
TANAKA, Junya et al. (21st Floor, Nakanoshima Intes Bldg. 6-2-40, Nakanoshima, Kita-ku, Osaka-sh, Osaka 05, 〒5300005, JP)
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