Title:
ADHESION PREVENTION MATERIAL
Document Type and Number:
WIPO Patent Application WO/2019/078349
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an adhesion prevention material capable of exhibiting excellent adhesion preventive effect. This adhesion prevention material concurrently uses: (A) a peptide (A-1) having an amino acid sequence ―(X―Pro―Y)n― [wherein X represents an arbitrary defined amino acid, Pro represents proline, Y represents hydroxyproline or proline, and n is an integer between 1 and 10] and/or a peptide (A-2) having an amino acid sequence ―(Pro―Y)m― [wherein Pro represents proline, Y represents hydroxyproline or proline, and m is an integer between 1-10]; and (B) a gelatin gel. This adhesion prevention material exhibits a dramatically enhanced adhesion preventive effect as compared with the case where the abovementioned components are used individually, and in particular, has a markedly superior effect against adhesion of tendons.
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Inventors:
FUJII NAMIKI (JP)
YOSHIOKA YUICHIRO (JP)
FUKUDA TATSURU (JP)
YOSHIOKA YUICHIRO (JP)
FUKUDA TATSURU (JP)
Application Number:
PCT/JP2018/038977
Publication Date:
April 25, 2019
Filing Date:
October 19, 2018
Export Citation:
Assignee:
OTSUKA PHARMA FACTORY INC (JP)
International Classes:
A61L31/06; A61L31/04; A61L31/14; C07K5/078; C07K5/08; C07K5/083; C07K14/78
Domestic Patent References:
WO1998022157A1 | 1998-05-28 | |||
WO2013077414A1 | 2013-05-30 |
Foreign References:
JP2000271207A | 2000-10-03 | |||
JPH10113384A | 1998-05-06 | |||
JP2013223644A | 2013-10-31 | |||
JPH08500334A | 1996-01-16 | |||
JPH0852204A | 1996-02-27 | |||
JP2004065780A | 2004-03-04 | |||
JP2013112653A | 2013-06-10 | |||
JP2013112653A | 2013-06-10 | |||
JPH09103479A | 1997-04-22 |
Other References:
ALBERTS, B. ET AL.: "Passage, Molecular Biology of the Cells", PASSAGE, MOLECULAR BIOLOGY OF THE CELLS; 5TH ED. 3RD PRINT, 20 October 2011 (2011-10-20), pages 1184 - 1185, XP009520473, Retrieved from the Internet
See also references of EP 3701976A4
See also references of EP 3701976A4
Attorney, Agent or Firm:
TANAKA, Junya et al. (JP)
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