ADHESIVE PATCH - HISAMITSU PHARMACEUTICAL CO

Title:

ADHESIVE PATCH

Document Type and Number:

WIPO Patent Application WO/2018/198924

Kind Code:

A1

Abstract:

An adhesive patch which is provided with a support layer and an adhesive layer, and wherein: the adhesive layer contains at least one substance selected from the group consisting of butorphanol and pharmaceutically acceptable salts thereof, a rubber-based adhesive base agent and a silicone-based adhesive base agent; and the mass ratio of the rubber-based adhesive base agent to the silicone-based adhesive base agent in the adhesive layer, namely (mass of rubber-based adhesive base agent):(mass of silicone-based adhesive base agent) is from 9.5:0.5 to 1.9:8.1.

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Inventors:

KOMINAMI KAZUYA (JP)
SHIMA TAKITO (JP)
UCHIDA NAOYUKI (JP)
FUJITA NAOKO (JP)
SUZUKI SHIGEO (JP)
KAIHO TERUMITSU (JP)

Application Number:

PCT/JP2018/016115

Publication Date:

November 01, 2018

Filing Date:

April 19, 2018

Export Citation:

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Assignee:

HISAMITSU PHARMACEUTICAL CO (JP)

International Classes:

A61K31/485; A61K9/70; A61K47/22; A61K47/32; A61K47/34; A61P25/04

Domestic Patent References:

WO2016060122A1	2016-04-21
WO2005102393A1	2005-11-03
WO2016060122A1	2016-04-21

Foreign References:

JPH0753357A	1995-02-28
JPS6183116A	1986-04-26
US3775414A	1973-11-27

Other References:

SVOZIL, MICHAL ET AL.: "In vitro studies on transdermal permeation of butorphanol", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 33, 2007, pages 559 - 567, XP055527449, ISSN: 0363-9045
M. SVOZIL ET AL., DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 33, no. 5, 2007, pages 559 - 567
"Pharmaceutical Excipients Directory", 2016
See also references of EP 3616698A4