Title:
ADIPOSE-DERIVED STEM CELL SHEET FOR TRANSPLANTATION HAVING INCREASED ANGIOGENESIS THROUGH THREE-DIMENSIONAL CO-CULTURE, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2020/101185
Kind Code:
A1
Abstract:
The present invention relates to: an adipose-derived stem cell sheet containing three-dimensional spherical cells, wherein three-dimensional spherical cells of adipose-derived stem cells are co-cultured on a sheet composed of the adipose-derived stem cells; and a method for producing same. When the adipose-derived stem cell sheet containing three-dimensional spherical cells according to the present invention is transplanted into a patient having an ischemic disease, a high stem cell engraftment rate and angiogenesis are exhibited, and thus the adipose-derived stem cell sheet is considered to be effective for treating ischemic diseases.
Inventors:
LIM DO-SUN (KR)
JOO HYUNG JOON (KR)
KIM JONG-HO (KR)
JOO HYUNG JOON (KR)
KIM JONG-HO (KR)
Application Number:
PCT/KR2019/013480
Publication Date:
May 22, 2020
Filing Date:
October 15, 2019
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
C12N5/0775; A61K35/28; A61P9/10
Foreign References:
| EP1690929A1 | 2006-08-16 | |||
| KR20170104917A | 2017-09-18 | |||
| KR20100061455A | 2010-06-07 | |||
| US20100166714A1 | 2010-07-01 | |||
| US20090047738A1 | 2009-02-19 |
Other References:
KRETZSCHMAR, KAI: "Organoids: modeling development and the stem cell niche in a dish", DEVELOPMENTAL CELL, vol. 38, 2016, pages 590 - 600, XP029749729, DOI: 10.1016/j.devcel.2016.08.014
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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