Title:
ADSORBENT FOR ADVANCED GLYCATION ENDPRODUCTS
Document Type and Number:
WIPO Patent Application WO/2007/037554
Kind Code:
A1
Abstract:
The invention aims at providing an adsorbent having excellent adsorptivity for advanced glycation endproducts (AGEs). The invention provides an adsorbent for AGEs consisting of a copolymer resin comprising hydrophilic methacrylate units, which resin is composed of constituent units derived from a specific methacrylate and constituent units derived from a vinyl monomer. It is preferable that the copolymer resin have basic ion-exchange groups.
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Inventors:
INOUE HIROYOSHI (JP)
Application Number:
PCT/JP2006/320042
Publication Date:
April 05, 2007
Filing Date:
September 29, 2006
Export Citation:
Assignee:
UNIV KURUME (JP)
INOUE HIROYOSHI (JP)
INOUE HIROYOSHI (JP)
International Classes:
A61K31/787; A61M1/36; A61P3/10; A61P7/08; A61P9/10; A61P13/12; A61P19/02; A61P25/28; A61P27/02; A61P29/00; B01J20/26; C08F212/14; C08F220/32; C08F222/20; C08F226/06
Foreign References:
| JP2005139414A | 2005-06-02 | |||
| JP2001316420A | 2001-11-13 | |||
| JP2001004624A | 2001-01-12 | |||
| JPS5949773A | 1984-03-22 | |||
| JP2004300153A | 2004-10-28 | |||
| JP2004529126A | 2004-09-24 | |||
| JP2005139414A | 2005-06-02 |
Other References:
INOUE H. AND YAMAGUCHI S.: "Design of a New Phosphate Binder, Anion Exchange Resin, Based on Microcalorimeter Measurements", LETTERS IN DRUG DESIGN & DISCOVERY, vol. 2, May 2005 (2005-05-01), pages 250 - 254, XP003011089
INOUE H.: "In-ion Kokan Jushi ni yoru Shoka Kannai Shokumotsusei Rinsan no Kyuchaku", JOURNAL OF THE CHEMICAL SOCIETY OF JAPAN, no. 1, 2000, pages 19 - 23, XP003011090
RANDOUX C. ET AL.: "Filtration of native and glycated beta2-microglobulin by charged and neutral dialysis membranes", KIDNEY INTERNATIONAL, vol. 60, no. 4, October 2001 (2001-10-01), pages 1571 - 1577, XP003011091
H. INOUE; S. YAMAGISHI, LETTERS IN DRUG DESIGN & DISCOVERY, vol. 2, no. 3, 2005, pages 250 - 254
TAKEUCHI ET AL., MOL. MED., vol. 7, 2001, pages 783
See also references of EP 1944034A4
INOUE H.: "In-ion Kokan Jushi ni yoru Shoka Kannai Shokumotsusei Rinsan no Kyuchaku", JOURNAL OF THE CHEMICAL SOCIETY OF JAPAN, no. 1, 2000, pages 19 - 23, XP003011090
RANDOUX C. ET AL.: "Filtration of native and glycated beta2-microglobulin by charged and neutral dialysis membranes", KIDNEY INTERNATIONAL, vol. 60, no. 4, October 2001 (2001-10-01), pages 1571 - 1577, XP003011091
H. INOUE; S. YAMAGISHI, LETTERS IN DRUG DESIGN & DISCOVERY, vol. 2, no. 3, 2005, pages 250 - 254
TAKEUCHI ET AL., MOL. MED., vol. 7, 2001, pages 783
See also references of EP 1944034A4
Attorney, Agent or Firm:
NANJO, Hiromichi (Okina Bldg. 2-9, Nishitenma 3-chome, Kita-k, Osaka-shi Osaka 47, JP)
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