Title:
ADSORBENT FOR ORAL ADMINISTRATION, THERAPEUTIC AGENT FOR RENAL DISEASES AND THERAPEUTIC AGENT FOR HEPATIC DISEASES
Document Type and Number:
WIPO Patent Application WO/2016/031908
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an adsorbent for oral administration, said adsorbent being capable of adsorbing a large amount of indole in the presence of bile acid.
The problem can be solved by providing the adsorbent for oral administration according to the present invention that is characterized by comprising a spherical activated carbon, said spherical activated carbon having a specific surface area determined by the BET method of 800 m2/g or more, a bulk density of 0.3-0.8 g/mL, and a pore volume, relative to pores with a pore diameter of less than 3 nm, of 0.3 mL/g or more, and showing a micropore/mesopore ratio (Vm) determined by formula (1): Vm=Vmic/Vmet [wherein: Vmic stands for the pore volume of pores with a pore diameter of less than 3 nm; and Vmet stands for pore volume of pores with a pore diameter of 3-50 nm] of 3.0 or more.
Inventors:
HONDA KAORU (JP)
HIGASHIYAMA YUKIHIRO (JP)
WAKAHOI TAKASHI (JP)
HIGASHIYAMA YUKIHIRO (JP)
WAKAHOI TAKASHI (JP)
Application Number:
PCT/JP2015/074213
Publication Date:
March 03, 2016
Filing Date:
August 27, 2015
Export Citation:
Assignee:
KUREHA CORP (JP)
International Classes:
A61K33/44; A61P1/16; A61P13/12; A61P39/02
Domestic Patent References:
| WO2010086985A1 | 2010-08-05 | |||
| WO2013051680A1 | 2013-04-11 | |||
| WO2014129614A1 | 2014-08-28 |
Foreign References:
| JP2005314415A | 2005-11-10 | |||
| JP2006131461A | 2006-05-25 |
Other References:
See also references of EP 3187187A4
Attorney, Agent or Firm:
MORITA Kenichi et al. (JP)
Ken-ichi Morita (JP)
Ken-ichi Morita (JP)
Download PDF: