Title:
AFFINITY DISSOCIATION MATRIX FOR IMMUNOGLOBULIN PURIFICATION USE
Document Type and Number:
WIPO Patent Application WO/2018/180205
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a novel affinity dissociation matrix which has bindability to an immunoglobulin and has excellent chemical stability toward an alkaline solution; and a method for producing an immunoglobulin using the affinity dissociation matrix. The affinity dissociation matrix according to the present invention is characterized in that a novel peptide is used as a ligand, wherein the novel peptide is based on the amino acid sequence for a protein that has a high amino acid sequence identity to an immunoglobulin binding domain of protein G but is unknown about the difference in physical properties and functions from protein G.
Inventors:
YOSHIDA SHINICHI (JP)
Application Number:
PCT/JP2018/008051
Publication Date:
October 04, 2018
Filing Date:
March 02, 2018
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
B01D15/38; C07K17/00; B01J20/281; C07K1/22; C07K14/315; C07K19/00
Domestic Patent References:
| WO2014071234A1 | 2014-05-08 | |||
| WO2015030094A1 | 2015-03-05 | |||
| WO2016061427A1 | 2016-04-21 | |||
| WO2015030094A1 | 2015-03-05 | |||
| WO2016061427A1 | 2016-04-21 |
Foreign References:
| JP2013521258A | 2013-06-10 | |||
| JP2009195184A | 2009-09-03 | |||
| JP2016079153A | 2016-05-16 | |||
| JPS63503032A | 1988-11-10 | |||
| JP2009195184A | 2009-09-03 | |||
| JP2016079153A | 2016-05-16 | |||
| JP2017071909A | 2017-04-13 |
Other References:
JONSSON, H. ET AL.: "A protein G-related cell surface protein in Streptococcus zooepidemicus", INFECTION AND IMMUNITY, vol. 63, no. 8, 1995, pages 2968 - 2975, XP055556603
GULICH, S. ET AL.: "Engineering streptococcal protein G for increased alkaline stability", PROTEIN ENGINEERING, vol. 15, no. 10, 2002, pages 835 - 842, XP055556609, Retrieved from the Internet
PALMER, B. ET AL.: "Design of stability at extreme alkaline pH in streptococcal protein G", J. BIOTECHNOL., vol. 134, 2008, pages 222 - 230, XP022587995
HOBER S. ET AL., J. CHROMATOGR. B, vol. 848, 2007, pages 40 - 47
SHUKLA A. A. ET AL., TRENDS BIOTECHNOL., vol. 28, 2010, pages 253 - 261
BOUVET P. J. ET AL., INT. J. IMMUNOPHARMAC., vol. 16, 1994, pages 419 - 424
DERRICK J. P ET AL., NATURE, vol. 359, 1992, pages 752 - 754
BAILEY L. J. ET AL., J. IMMUNOL. METHODS, vol. 415, 2014, pages 24 - 30
LINHULT M. ET AL., PROTEINS, vol. 55, 2004, pages 407 - 416
GULICH S. ET AL., PROTEIN ENG., vol. 15, 2002, pages 835 - 842
PALMER B. ET AL., J. BIOTECHNOL., vol. 134, 2008, pages 222 - 230
JONSSON HLINDMARK HGUSS B., INFECT IMMUN., vol. 8, 1995, pages 2968 - 75
NAGATA ET AL.: "Real-Time Analysis Experimental Method for Interaction Between Biological Substances", 1998, SPRINGER-VERLAG TOKYO, pages: 41
See also references of EP 3604341A4
GULICH, S. ET AL.: "Engineering streptococcal protein G for increased alkaline stability", PROTEIN ENGINEERING, vol. 15, no. 10, 2002, pages 835 - 842, XP055556609, Retrieved from the Internet
PALMER, B. ET AL.: "Design of stability at extreme alkaline pH in streptococcal protein G", J. BIOTECHNOL., vol. 134, 2008, pages 222 - 230, XP022587995
HOBER S. ET AL., J. CHROMATOGR. B, vol. 848, 2007, pages 40 - 47
SHUKLA A. A. ET AL., TRENDS BIOTECHNOL., vol. 28, 2010, pages 253 - 261
BOUVET P. J. ET AL., INT. J. IMMUNOPHARMAC., vol. 16, 1994, pages 419 - 424
DERRICK J. P ET AL., NATURE, vol. 359, 1992, pages 752 - 754
BAILEY L. J. ET AL., J. IMMUNOL. METHODS, vol. 415, 2014, pages 24 - 30
LINHULT M. ET AL., PROTEINS, vol. 55, 2004, pages 407 - 416
GULICH S. ET AL., PROTEIN ENG., vol. 15, 2002, pages 835 - 842
PALMER B. ET AL., J. BIOTECHNOL., vol. 134, 2008, pages 222 - 230
JONSSON HLINDMARK HGUSS B., INFECT IMMUN., vol. 8, 1995, pages 2968 - 75
NAGATA ET AL.: "Real-Time Analysis Experimental Method for Interaction Between Biological Substances", 1998, SPRINGER-VERLAG TOKYO, pages: 41
See also references of EP 3604341A4
Attorney, Agent or Firm:
UEKI, Kyuichi et al. (JP)
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