Title:
AFFINITY-SEPARATION MATRIX FOR PEPTIDE CONTAINING Fab REGION
Document Type and Number:
WIPO Patent Application WO/2016/031902
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an affinity-separation matrix having excellent binding capacity and retention ability with respect to an IgG Fab-region-containing peptide, and to provide a method for manufacturing a Fab-region-containing peptide using the affinity-separation matrix. The affinity-separation matrix pertaining to the present invention is characterized in that a Fab-region-binding peptide is immobilized as a ligand on a water-insoluble carrier at a density of at least 1.0 mg/mL-gel.
Inventors:
MURATA DAI (JP)
YOSHIDA SHINICHI (JP)
YOSHIDA SHINICHI (JP)
Application Number:
PCT/JP2015/074176
Publication Date:
March 03, 2016
Filing Date:
August 27, 2015
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
C07K1/22; C07K17/00; C12N15/09
Domestic Patent References:
| WO1997026930A1 | 1997-07-31 | |||
| WO2015030094A1 | 2015-03-05 | |||
| WO1998001560A1 | 1998-01-15 | |||
| WO2013041730A1 | 2013-03-28 |
Foreign References:
| JPH03128400A | 1991-05-31 | |||
| JP2008523140A | 2008-07-03 | |||
| JP2009195184A | 2009-09-03 |
Other References:
BAILEY LJ. ET AL.: "Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.", J. IMMUNOL. METHODS, vol. 415, 22 October 2014 (2014-10-22), pages 24 - 30, XP029103011, DOI: doi:10.1016/j.jim.2014.10.003
Attorney, Agent or Firm:
UEKI, Kyuichi et al. (JP)
Hisakazu Ueki (JP)
Hisakazu Ueki (JP)
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