AFLATOXIN PRODUCTION INHIBITOR, AND METHOD FOR CONTROL OF AFLATOXIN POISONING USING THE SAME

WIPO Patent Application WO/2006/137297

A1

Disclosed are: an aflatoxin production inhibitor which can inhibit the production of aflatoxin specifically and effectively and is highly safe and practically useful; a process for producing the inhibitor with good efficiency; and a method for controlling the aflatoxin poisoning using the aflatoxin production inhibitor. An aflatoxin production inhibitor comprising at least one of a dioctane represented by the structural formula (I): (I) wherein R represents a hydrogen or a methyl group, and a derivative thereof as an active ingredient; a process for preparing an aflatoxin production inhibitor by culturing a dioctane-producing bacterium and then performing a method for separation/purification of the aflatoxin production inhibitor from a culture by centrifugal liquid-liquid partition chromatography or by chemical synthesis; and a method for controlling the aflatoxin poisoning comprising inhibiting the production of aflatoxin by an aflatoxin-producing bacterium using the aflatoxin production inhibitor.

SAKUDA SHOHEI (JP)
NAKAMURA KEITA (JP)
AKIYAMA TETSUO (JP)
TAKAHASHI YOSHIKAZU (JP)
MURAOKA YASUHIKO (JP)
KURATA IKUKO (JP)

PCT/JP2006/311881

December 28, 2006

June 13, 2006

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MICROBIAL CHEM RES FOUND (JP)
UNIV TOKYO (JP)
SAKUDA SHOHEI (JP)
NAKAMURA KEITA (JP)
AKIYAMA TETSUO (JP)
TAKAHASHI YOSHIKAZU (JP)
MURAOKA YASUHIKO (JP)
KURATA IKUKO (JP)

A01N37/46; A01N63/02; A01P3/00; C12P13/02; C12R1/465

JPH0377857A	1991-04-03
JPH09241167A	1997-09-16
JPH1179911A	1999-03-23
JP2001139507A	2001-05-22

Hirota, Koichi (NAGARE & ASSOCIATES 4th Floor, Shinjuku TR Bldg., 2-2-13, Yoyogi, Shibuya-k, Tokyo 53, JP)

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