AGENT FOR IMPROVING BACTERIAL FLORA IN ORAL CAVITY AND ORAL COMPOSITION

Title:

AGENT FOR IMPROVING BACTERIAL FLORA IN ORAL CAVITY AND ORAL COMPOSITION

Document Type and Number:

WIPO Patent Application WO/2019/208699

Kind Code:

A1

Abstract:

Provided are an agent for improving bacterial flora in the oral cavity, said agent selectively inhibiting the growth of periodontal disease-causing bacteria in the oral cavity and selectively promoting the growth of non-pathogenic bacteria to thereby improve the balance of the bacterial flora, and an oral composition comprising the agent. An agent for improving bacterial flora in the oral cavity which comprises (A) one or more members selected from among spermine, spermidine, sialic acid and lactoferrin, and (B) one or more members selected from among lactulose, an oligosaccharide and a sialic acid-containing disaccharide, and an oral composition which comprises the agent as an active ingredient. An oral composition which comprises one or more members selected from among spermine, spermidine and sialic acid as component (A) and the aforesaid component (B); an oral composition which comprises lactoferrin as component (A) and (B-3) a sialic acid-containing disaccharide as component (B); and an oral composition which comprises lactoferrin as component (A) and (B-1) one or more members selected from among lactulose and an oligosaccharide as component (B).

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Inventors:

TAKIMOTO YUNA (JP)
MARUYAMA MASATO (JP)
MORISHIMA SEIJI (JP)
TAKEDA KAORI (JP)

Application Number:

PCT/JP2019/017652

Publication Date:

October 31, 2019

Filing Date:

April 25, 2019

Export Citation:

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Assignee:

LION CORP (JP)

International Classes:

A61K8/41; A23G3/34; A23G4/00; A23L2/52; A61K8/60; A61K8/64; A61K8/73; A61K31/132; A61K31/7012; A61K31/7016; A61K31/702; A61K38/40; A61P1/02; A61Q11/00

Domestic Patent References:

WO2017147540A1	2017-08-31
WO2019026997A1	2019-02-07

Foreign References:

CN106490285A	2017-03-15
JP2016138043A	2016-08-04
JP2015030688A	2015-02-16
JP2012097036A	2012-05-24
JP2017075130A	2017-04-20
JP2016503807A	2016-02-08
JP2010275398A	2010-12-09
US20140056951A1	2014-02-27

Attorney, Agent or Firm:

PATENT PROFESSIONAL CORPORATION EI-MEI PATENT OFFICE (JP)

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