Title:
AGENT FOR PREVENTING MUSCULAR ATROPHY
Document Type and Number:
WIPO Patent Application WO/2011/108692
Kind Code:
A1
Abstract:
Disclosed is an agent for preventing muscular atrophy, which has an excellent preventive effect on muscular atrophy and comprises a whey protein hydrolysate.
Specifically disclosed is an agent for preventing muscular atrophy, which comprises a whey protein hydrolysate, wherein the whey protein hydrolysate has a molecular weight distribution of 10 kDa or less (wherein the main peak appears at 200 Da to 3 kDa), an APL (average peptide chain length) of 2 to 8, a free amino acid content of 20% or less relative to the total amount of all of the constituents, a branched amino acid content of 20% or more, and antigenicity that is 1/100,000 or lower of the antigenicity of β-lactoglobulin.
Inventors:
MIURA SUSUMU (JP)
NAITO HISASHI (JP)
NAITO HISASHI (JP)
Application Number:
PCT/JP2011/055037
Publication Date:
September 09, 2011
Filing Date:
March 04, 2011
Export Citation:
Assignee:
SNOW BRAND MILK PRODUCTS CO LTD (JP)
MIURA SUSUMU (JP)
NAITO HISASHI (JP)
MIURA SUSUMU (JP)
NAITO HISASHI (JP)
International Classes:
A61K38/00; A23L1/305; A61K35/20; A61P21/00; A61P21/04; A61P43/00; A23C21/00
Domestic Patent References:
| WO2008111562A1 | 2008-09-18 |
Foreign References:
| JP2008255090A | 2008-10-23 | |||
| JPH02138991A | 1990-05-28 |
Other References:
TANG, J.E. ET AL.: "Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men", J APPL PHYSIOL, vol. 107, no. 3, 2009, pages 987 - 992, XP008168227
RENNIE, M.J. ET AL.: "Control of the size of the human muscle mass", ANNU REV PHYSIOL, vol. 66, 2004, pages 799 - 828, XP055112241
MORIFUJI, M. ET AL.: "Post-exercise carbohydrate plus whey protein hydrolysates supplementation increases skeletal muscle glycogen level in rats", AMINO ACIDS, vol. 38, no. 4, 11 July 2009 (2009-07-11), pages 1109 - 1115, XP019805409
TADA ET AL., SOY PROTEIN RESEARCH, vol. 2, 1999, pages 112 - 117
PADDON-JONES ET AL., AM J. CLIN. NUTR., vol. 87, 2008, pages 1562S - 6S
JAPANESE JOURNAL OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY, vol. 1, 1987, pages 36
RENNIE, M.J. ET AL.: "Control of the size of the human muscle mass", ANNU REV PHYSIOL, vol. 66, 2004, pages 799 - 828, XP055112241
MORIFUJI, M. ET AL.: "Post-exercise carbohydrate plus whey protein hydrolysates supplementation increases skeletal muscle glycogen level in rats", AMINO ACIDS, vol. 38, no. 4, 11 July 2009 (2009-07-11), pages 1109 - 1115, XP019805409
TADA ET AL., SOY PROTEIN RESEARCH, vol. 2, 1999, pages 112 - 117
PADDON-JONES ET AL., AM J. CLIN. NUTR., vol. 87, 2008, pages 1562S - 6S
JAPANESE JOURNAL OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY, vol. 1, 1987, pages 36
Attorney, Agent or Firm:
MOEGI PATENT OFFICE (JP)
Patent business corporation It burns and is ぎ特許事務所. (JP)
Patent business corporation It burns and is ぎ特許事務所. (JP)
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Claims: