Title:
AGENT FOR PREVENTING AND/OR TREATING PERIPHERAL NEUROPATHIC PAIN CAUSED BY ANTI-CANCER DRUG
Document Type and Number:
WIPO Patent Application WO/2013/179910
Kind Code:
A1
Abstract:
A medicine effective in preventing and/or treating peripheral neuropathic pain, such as allodynia, caused by an anti-cancer drug treatment; wherein the medicine contains thrombomodulin as an active ingredient.
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Inventors:
KAWABATA ATSUFUMI (JP)
SUZUKI HIDEAKI (JP)
SUZUKI HIDEAKI (JP)
Application Number:
PCT/JP2013/063743
Publication Date:
December 05, 2013
Filing Date:
May 17, 2013
Export Citation:
Assignee:
UNIV KINKI (JP)
ASAHI KASEI PHARMA CORP (JP)
ASAHI KASEI PHARMA CORP (JP)
International Classes:
A61K31/337; A61K38/55; A61P25/04; C07K14/47; C12N15/09
Domestic Patent References:
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| WO1988009811A1 | 1988-12-15 |
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| JP2012001543A | 2012-01-05 | |||
| JPH0920677A | 1997-01-21 | |||
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Other References:
NOBUAKI EGASHIRA ET AL., FOLIA PHARMACOL.JPN, vol. 136, no. 5, 2010, pages 275 - 279, XP008175707
DR. ELLEN SMITH ET AL.: "Treating Pain from Chemotherapy-induced Peripheral Neuropathy", NCL CANCER BULLETIN, vol. 7, no. 4, 23 February 2010 (2010-02-23), pages 7, XP008176159
SARAH J.L. FLATTERS ET AL.: "Acetyl-1-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy", NEUROSCIENCE LETTERS, vol. 397, no. 3, 2006, pages 219 - 223, XP027886015
PATRICK M. DOUGHERTY ET AL.: "Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients", PAIN, vol. 109, no. 1-2, 2004, pages 132 - 142, XP055179393
JUN'ICHI TANAKA ET AL., JOURNAL OF JAPANESE ASSOCIATION FOR ACUTE MEDICINE, vol. 23, no. 10, 15 October 2012 (2012-10-15), pages 457, XP008176059
NCI CANCER BULLETIN, vol. 7, no. 4, 23 February 2010 (2010-02-23)
FOLIA PHARMACOLOGICA JAPONICA, vol. 136, 2010, pages 275 - 279
EMBO JOURNAL, vol. 6, 1987, pages 1891 - 1897
THROMBOSIS AND HAEMOSTASIS, vol. 70, no. 3, 1993, pages 418 - 422
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 264, no. 9, 1989, pages 4872 - 4876
BLOOD, vol. 112, 2008, pages 3361 - 3670
THE JOURNAL OF CLINICAL INVESTIGATION, vol. 115, no. 5, 2005, pages 1267 - 1274
"Methods of Researches on Glycoprotein Sugar Chains", vol. 23, 1990, JAPAN SCIENTIFIC SOCIETIES PRESS, article "Biochemical Experimental Methods"
"Lecture of New Biochemical Experiments, Sugar I, Glycoprotein (Book 1)", vol. 3, 1990, TOKYO KAGAKU DOJIN
MULLIGAN R.C. ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 78, 1981, pages 2072 - 2076
HOWLEY P.M ET AL.: "Methods in Emzymology", vol. 101, 1983, ACADEMIC PRESS, pages: 387 - 402
J. BIOL. CHEM., vol. 264, 1989, pages 10351 - 10353
ZOLLER M.J. ET AL.: "Method in Enzymology", vol. 100, 1983, ACADEMIC PRESS, pages: 468 - 500
TAKEICHI HORIO: "TanpakushitsulKoso no Kiso Jikken Ho (Fundamental Experimental Methods for Proteins and Enzymes)", 1981
GOMI K. ET AL., BLOOD, vol. 75, 1990, pages 1396 - 1399
RANDALL LO. ET AL., ARCH. INT. PHARMACODYN. THER., vol. 111, 1957, pages 409 - 419
See also references of EP 2857037A4
DR. ELLEN SMITH ET AL.: "Treating Pain from Chemotherapy-induced Peripheral Neuropathy", NCL CANCER BULLETIN, vol. 7, no. 4, 23 February 2010 (2010-02-23), pages 7, XP008176159
SARAH J.L. FLATTERS ET AL.: "Acetyl-1-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy", NEUROSCIENCE LETTERS, vol. 397, no. 3, 2006, pages 219 - 223, XP027886015
PATRICK M. DOUGHERTY ET AL.: "Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients", PAIN, vol. 109, no. 1-2, 2004, pages 132 - 142, XP055179393
JUN'ICHI TANAKA ET AL., JOURNAL OF JAPANESE ASSOCIATION FOR ACUTE MEDICINE, vol. 23, no. 10, 15 October 2012 (2012-10-15), pages 457, XP008176059
NCI CANCER BULLETIN, vol. 7, no. 4, 23 February 2010 (2010-02-23)
FOLIA PHARMACOLOGICA JAPONICA, vol. 136, 2010, pages 275 - 279
EMBO JOURNAL, vol. 6, 1987, pages 1891 - 1897
THROMBOSIS AND HAEMOSTASIS, vol. 70, no. 3, 1993, pages 418 - 422
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 264, no. 9, 1989, pages 4872 - 4876
BLOOD, vol. 112, 2008, pages 3361 - 3670
THE JOURNAL OF CLINICAL INVESTIGATION, vol. 115, no. 5, 2005, pages 1267 - 1274
"Methods of Researches on Glycoprotein Sugar Chains", vol. 23, 1990, JAPAN SCIENTIFIC SOCIETIES PRESS, article "Biochemical Experimental Methods"
"Lecture of New Biochemical Experiments, Sugar I, Glycoprotein (Book 1)", vol. 3, 1990, TOKYO KAGAKU DOJIN
MULLIGAN R.C. ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 78, 1981, pages 2072 - 2076
HOWLEY P.M ET AL.: "Methods in Emzymology", vol. 101, 1983, ACADEMIC PRESS, pages: 387 - 402
J. BIOL. CHEM., vol. 264, 1989, pages 10351 - 10353
ZOLLER M.J. ET AL.: "Method in Enzymology", vol. 100, 1983, ACADEMIC PRESS, pages: 468 - 500
TAKEICHI HORIO: "TanpakushitsulKoso no Kiso Jikken Ho (Fundamental Experimental Methods for Proteins and Enzymes)", 1981
GOMI K. ET AL., BLOOD, vol. 75, 1990, pages 1396 - 1399
RANDALL LO. ET AL., ARCH. INT. PHARMACODYN. THER., vol. 111, 1957, pages 409 - 419
See also references of EP 2857037A4
Attorney, Agent or Firm:
SIKs & Co. (JP)
Patent business corporation patent firm Sykes (JP)
Patent business corporation patent firm Sykes (JP)
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