AGENT FOR PROMOTING IN VIVO ABSORPTION OF HYDROXYTYROSOL AND DERIVATIVES THEREOF AND USE OF SAME

WIPO Patent Application WO/2015/020138

A1

　The purpose of the present invention is to provide a means for promoting the in vivo absorption of hydroxytyrosol or a derivative thereof, prolonging the in vivo residence time, and sustaining the effect. As a result of in-depth studies, the present inventors discovered that the in vivo absorption of hydroxytyrosol or a derivative thereof can be promoted and the in vivo residence time can be prolonged by using hydroxytyrosol or a derivative thereof in combination with a compound having a galloyl group.

UENO TOSHIYA (JP)
KOMINAMI MASARU (JP)
KASAJIMA NAOKI (JP)

PCT/JP2014/070839

February 12, 2015

August 07, 2014

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SUNTORY HOLDINGS LTD (JP)

A61K31/05; A23L1/30; A61K31/353; A61K36/00; A61K36/18; A61K36/48; A61K36/73; A61P3/06; A61P3/10; A61P9/12; A61P29/00; A61P31/04; A61P39/06; A61P43/00

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PAZOS ET AL.: "Physiochemical properties of natural phenolics from grapes and olive oil byproducts and their antioxidant activity in frozen Horse mackerel fillets", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 54, 2006, pages 366 - 373, XP018020174
See also references of EP 3075379A4

ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)

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