Title:
AGENT FOR REDUCTION OF SCAR FORMATION BY USING WOUND ALKALINIZATION
Document Type and Number:
WIPO Patent Application WO2006074221
Kind Code:
A3
Abstract:
The present invention relates to an agent for reducing scar formation, which inhibits the scar formation by injecting sodium bicarbonate to the dermis tissue of the wound with a syringe to directly control pH of the wound site, namely, by alkalinizing the wound to inactivate TGF-ß. According to the present invention, the agent for reducing scar formation by controlling the wound healing process can be clinically and immediately applied to the treatment of tylosis scar and keloid, etc., and is effective to the treatment of intractable fibrosis diseases. Also, the invention can be widely applied in many ways as an easy tool which can control the action of TGF-ß in a living organism.
Inventors:
KEUM KI CHANG (KR)
YOO NAECHOON (KR)
YOO WON-MIN (KR)
YOO NAECHOON (KR)
YOO WON-MIN (KR)
Application Number:
PCT/US2006/000174
Publication Date:
September 28, 2006
Filing Date:
January 03, 2006
Export Citation:
Assignee:
CAMBRIDGEMED INC (US)
KEUM KI CHANG (KR)
YOO NAECHOON (KR)
YOO WON-MIN (KR)
KEUM KI CHANG (KR)
YOO NAECHOON (KR)
YOO WON-MIN (KR)
International Classes:
A61K33/14; A61F13/02; A61K33/00; A61K33/42
Foreign References:
| US6063406A | 2000-05-16 | |||
| US4659572A | 1987-04-21 | |||
| US5209724A | 1993-05-11 |
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