Title:
AGENT FOR SUPPRESSION OF GASTRIC EMPTYING COMPRISING 4-HYDROXYISOLEUCINE
Document Type and Number:
WIPO Patent Application WO/2008/044770
Kind Code:
A1
Abstract:
Disclosed are an agent for suppressing the gastric emptying and an anorexigenic agent which are more effective. The agent for suppressing the gastric emptying comprises 4-hydroxyisoleucine or a salt thereof. The anorexigenic agent comprises 4-hydroxyisoleucine or a salt thereof.
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Inventors:
KONISHI ATSUSHI (JP)
ISHIBASHI IKUMI (JP)
KITAHARA YOSHIRO (JP)
MIURA KYOKO (JP)
NARASAKA SACHIKO (JP)
ISHIBASHI IKUMI (JP)
KITAHARA YOSHIRO (JP)
MIURA KYOKO (JP)
NARASAKA SACHIKO (JP)
Application Number:
PCT/JP2007/069991
Publication Date:
April 17, 2008
Filing Date:
October 12, 2007
Export Citation:
Assignee:
AJINOMOTO KK (JP)
KONISHI ATSUSHI (JP)
ISHIBASHI IKUMI (JP)
KITAHARA YOSHIRO (JP)
MIURA KYOKO (JP)
NARASAKA SACHIKO (JP)
KONISHI ATSUSHI (JP)
ISHIBASHI IKUMI (JP)
KITAHARA YOSHIRO (JP)
MIURA KYOKO (JP)
NARASAKA SACHIKO (JP)
International Classes:
A61K31/198; A23L1/305; A23L27/10; A23L33/20; A61P1/00; A61P3/04; A61P43/00
Domestic Patent References:
| WO2005049006A1 | 2005-06-02 |
Foreign References:
| JP2006089449A | 2006-04-06 | |||
| US20060199853A1 | 2006-09-07 | |||
| JP2006280713A | 2006-10-19 |
Other References:
YAMAGUCHI K.: "Fenugreek Ekisu (Promilin) no Atarashii Seiri Kassei", FOOD PROCESSING AND INGREDIENTS, vol. 39, no. 8, 2004, pages 51 - 53, XP003022181
YOSHIDA T.: "Drug treatment of obesity", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 53, 1995, pages 481 - 486, XP003022182
JONES K.L. ET AL.: "Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects", DIABETES CARE, vol. 22, no. 2, February 1999 (1999-02-01), pages 339 - 344, XP003022183
See also references of EP 2078523A4
Z. MADAR ET AL., EUR. J. CLIN. NUTR., vol. 42, no. 1, 1988, pages 51 - 4
P. PETIT ET AL., PHARMACOL. BIOCHEM. BEHAV., vol. 45, no. 2, 1993, pages 369 - 74
R. D. SHARMA ET AL., EUR. J. CLIN. NUTR., vol. 44, no. 4, 1990, pages 301 - 6
T. HANDA ET AL., BIOSCI. BIOTECHNOL. BIOCHEM., vol. 69, no. 6, 2005, pages 1186 - 8
Y. SAUVAIRE ET AL., DIABETES, vol. 47, no. 2, 1998, pages 206 - 10
C. BROCA ET AL., AM. J. PHYSIOL. 277 (ENDOCRINOL. METAB. 40), vol. 277, 1999, pages E617 - E623
M. BICKEL ET AL., INT. J. OBES., vol. 28, 2004, pages 211 - 221
YOSHIDA T.: "Drug treatment of obesity", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 53, 1995, pages 481 - 486, XP003022182
JONES K.L. ET AL.: "Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects", DIABETES CARE, vol. 22, no. 2, February 1999 (1999-02-01), pages 339 - 344, XP003022183
See also references of EP 2078523A4
Z. MADAR ET AL., EUR. J. CLIN. NUTR., vol. 42, no. 1, 1988, pages 51 - 4
P. PETIT ET AL., PHARMACOL. BIOCHEM. BEHAV., vol. 45, no. 2, 1993, pages 369 - 74
R. D. SHARMA ET AL., EUR. J. CLIN. NUTR., vol. 44, no. 4, 1990, pages 301 - 6
T. HANDA ET AL., BIOSCI. BIOTECHNOL. BIOCHEM., vol. 69, no. 6, 2005, pages 1186 - 8
Y. SAUVAIRE ET AL., DIABETES, vol. 47, no. 2, 1998, pages 206 - 10
C. BROCA ET AL., AM. J. PHYSIOL. 277 (ENDOCRINOL. METAB. 40), vol. 277, 1999, pages E617 - E623
M. BICKEL ET AL., INT. J. OBES., vol. 28, 2004, pages 211 - 221
Attorney, Agent or Firm:
TAKASHIMA, Hajime (1-1 Fushimimachi 4-chome, Chuo-ku, Osaka-sh, Osaka 44, JP)
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